VX-222

Base Information

• Chemical Name: VX-222
• CAS No.: 1026785-59-0
• Molecular Formula: C25H35NO4S
• Molecular Weight: 445.61
• Mol file: 1026785-59-0.mol

Synonyms:VX-222

Chemical Property of VX-222

Chemical Property:

• Boiling Point: 640.512 °C at 760 mmHg
• PKA: 3.67±0.10(Predicted)
• Flash Point: 341.17 °C
• PSA: 106.08000
• Density: 1.22 g/cm³
• LogP: 5.30670
• Solubility.: ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH

Purity/Quality:

99% ^*data from raw suppliers

5-(3,3-dimethyl-1-butyn-1-yl)-3-((cis-4-hydroxycyclohexyl)((trans-4-methylcyclohexyl)carbonyl)amino)-2-thiophenecarboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).
• Uses: VX-222, s a novel, potent and selective inhibitor of HCV polymerase .

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