Chemical Property of VX-222
Chemical Property:
- Boiling Point:640.512 °C at 760 mmHg
- PKA:3.67±0.10(Predicted)
- Flash Point:341.17 °C
- PSA:106.08000
- Density:1.22 g/cm3
- LogP:5.30670
- Solubility.:≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH
- Purity/Quality:
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99% *data from raw suppliers
VX-222 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM).
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Uses
VX-222, s a novel, potent and selective inhibitor of HCV polymerase .