C₂₂H₂₄O₅

Base Information

• Chemical Name: C₂₂H₂₄O₅
• CAS No.: 1426547-62-7
• Molecular Formula: C₂₂H₂₄O₅
• Molecular Weight: 368.43
• Mol file: 1426547-62-7.mol

Synonyms:

Chemical Property of C₂₂H₂₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄O₅

There total 11 articles about C₂₂H₂₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H22O5 (1426547-61-6) → C22H24O5 (1426547-62-7)

Guidance literature:

C₂₂H₂₂O₅; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

With Glauber's salt; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja311902f

Reference yield:

1-methyl-2-naphthol (1076-26-2) → C22H24O5 (1426547-62-7)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 8 h / 0 - 20 °C / Inert atmosphere

2.1: n-butyllithium / hexane; diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere

2.2: 0.17 h / 0 °C / Inert atmosphere

3.1: montmorillonite K-10 / benzene / 1 h / 20 °C

4.1: potassium carbonate / acetone / 4.5 h / 0 - 20 °C

5.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium phosphate / water; 1,2-dimethoxyethane / 3.5 h / Reflux

6.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

6.2: 1 h / 20 °C / Inert atmosphere

With potassium phosphate; lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium hydride; potassium carbonate; In tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; hexane; water; N,N-dimethyl-formamide; acetone; mineral oil; benzene; 5.1: |Suzuki Coupling;

DOI:10.1021/ja311902f

Reference yield:

3-(methoxymethoxy)-4-methyl-2-naphthaldehyde (1426547-58-1) → C22H24O5 (1426547-62-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: montmorillonite K-10 / benzene / 1 h / 20 °C

2.1: potassium carbonate / acetone / 4.5 h / 0 - 20 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium phosphate / water; 1,2-dimethoxyethane / 3.5 h / Reflux

4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

4.2: 1 h / 20 °C / Inert atmosphere

With potassium phosphate; lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; 1,2-dimethoxyethane; water; acetone; benzene; 3.1: |Suzuki Coupling;

DOI:10.1021/ja311902f

upstream raw materials:

2-hydroxynaphthalene-1-carbaldehyde

1-methyl-2-naphthol

2-(methoxymethoxy)-1-methylnaphthalene

3-(methoxymethoxy)-4-methyl-2-naphthaldehyde

Downstream raw materials:

2-(3-(methoxymethyl)-1-methylnaphthalen-2-yl)benzene-1,3-diol

C₂₃H₂₆O₅