cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran

Base Information

• Chemical Name: cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran
• CAS No.: 135614-83-4
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.275
• Mol file: 135614-83-4.mol

Synonyms:

Chemical Property of cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran

There total 1 articles about cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-phenyl-4-(allyloxy)cyclohexa-2,5-dienone (135614-80-1) → cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran (135614-83-4,135639-24-6)

Guidance literature:

(1,5-cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate; In tetrahydrofuran; for 12h; Ambient temperature;

DOI:10.1021/jo00021a037

Reference yield: 81.0%

cis- and trans-2-hydroxy-3-methyl-5-phenyldihydrobenzofuran (135614-83-4,135639-24-6) → 3-methyl-5-phenylbenzofuran (135614-84-5)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 5h; Heating;

DOI:10.1021/jo00021a037

upstream raw materials:

4-phenyl-4-(allyloxy)cyclohexa-2,5-dienone

Downstream raw materials:

3-methyl-5-phenylbenzofuran