2-bromo-1-(4-nitrophenyl)ethanol

Base Information

• Chemical Name: 2-bromo-1-(4-nitrophenyl)ethanol
• CAS No.: 19922-82-8
• Molecular Formula: C8H8BrNO3
• Molecular Weight: 246.06
• Mol file: 19922-82-8.mol

Synonyms:1-p-nitrophenyl-2-bromoethanol;Benzylalcohol,a-(bromomethyl)-o-chloro-(6CI);2-bromo-1-(para-nitrophenyl)-ethanol;1-(o-Chlorophenyl)-2-bromoethanol;2-bromo-1-(o-chlorophenyl)-ethanol;para-nitro-2-bromo-1-phenylethanol;2-Bromo-1-(2-chlorophenyl)ethan-1-ol;Benzenemethanol,a-(bromomethyl)-2-chloro;2-bromo-1-(4-nitro-phenyl)-ethanol;1-(2-CHLOROPHENYL)-2-BROMOETHANOL;2-Brom-1-(4-nitro-phenyl)-aethanol;

Chemical Property of 2-bromo-1-(4-nitrophenyl)ethanol

Chemical Property:

• Vapor Pressure: 5.41E-06mmHg at 25°C
• Melting Point: 86-87 °C
• Boiling Point: 365.8°C at 760 mmHg
• PKA: 12.26±0.20(Predicted)
• Flash Point: 175°C
• PSA: 66.05000
• Density: 1.69g/cm³
• LogP: 2.54630

Purity/Quality:

≥95% ^*data from raw suppliers

2-bromo-1-(4-nitrophenyl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromo-1-(4-nitrophenyl)ethanol

There total 8 articles about 2-bromo-1-(4-nitrophenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-Nitrophenacyl bromide (99-81-0) → 2-bromo-1-(4-nitrophenyl)ethanol (19922-82-8)

Guidance literature:

With sodium tetrahydroborate; In ethanol;

DOI:10.1021/jo00177a010

Reference yield:

4-Nitrophenacyl bromide (99-81-0) → (4-nitrophenyl)ethanone (100-19-6) + 2-bromo-1-(4-nitrophenyl)ethanol (19922-82-8)

Guidance literature:

With dibutylstannane; for 1h; Product distribution; Ambient temperature; p-dinitrobenzene (DNB) as additive; other temperature;

DOI:10.1016/S0040-4039(00)97070-9

Reference yield:

4-Nitrophenacyl bromide (99-81-0) → p-Nitrophenyloxirane (6388-74-5,38201-14-8,71884-55-4) + 2-bromo-1-(4-nitrophenyl)ethanol (19922-82-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 3h;

DOI:10.1016/S0957-4166(02)00222-7

upstream raw materials:

4-Nitrophenacyl bromide

4-nitrostyrene

(4-nitrophenyl)ethanone

p-Nitrophenyloxirane

Downstream raw materials:

2-(4-nitrophenyl)indolizine

4-Nitrophenacyl bromide

p-Nitrophenyloxirane

(2R)-2-(4-nitrophenyl)oxirane