BIS-ACV

Base Information

Chemical Name:BIS-ACV
CAS No.:69644-78-6
Molecular Formula:C₂₈H₄₈N₆O₁₂S₂
Molecular Weight:724.854
Hs Code.:
Mol file:69644-78-6.mol

Synonyms:

Suppliers and Price of BIS-ACV

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
Bis-ACV trifluoroacetate salt
2 mg
$ 200.00

Biosynth Carbosynth
Bis-ACV trifluoroacetate salt
1 mg
$ 125.00

Biosynth Carbosynth
Bis-ACV trifluoroacetate salt
25 mg
$ 725.00

Biosynth Carbosynth
Bis-ACV trifluoroacetate salt
10 mg
$ 450.00

Biosynth Carbosynth
Bis-ACV trifluoroacetate salt
5 mg
$ 300.00

AK Scientific
Bis-ACV
1mg
$ 218.00

Total 20 raw suppliers

Chemical Property of BIS-ACV

Chemical Property:

Storage Temp.:−20°C

Purity/Quality:

99%, ^*data from raw suppliers

Bis-ACV trifluoroacetate salt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

Useful:

Technology Process of BIS-ACV

There total 14 articles about BIS-ACV which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 87141-27-3
N-benzyloxycarbonyl-1-(p-nitrobenzyl)-δ-(L-α-aminoadipyl)-S-benzyl-L-cysteinyl-D-valine, benzhydryl ester

: 69644-78-6,94131-56-3
(S)-2-Amino-5-[(R)-2-[(R)-2-(5-amino-5-carboxy-pentanoylamino)-2-((R)-1-carboxy-2-methyl-propylcarbamoyl)-ethyldisulfanyl]-1-((R)-1-carboxy-2-methyl-propylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

: 21566-74-5,93133-50-7,141116-68-9,32467-88-2
(L-α-amino-δ-adipyl)-L-cysteinyl-D-valine

Guidance literature:: With ammonia; sodium;
DOI:10.1039/P19830000941

Reference yield:

: 84701-31-5,87422-32-0
di-(1-<(1R)-carboxy-2-methylpropyl>-(3R)-<-(5S)-5-amino-5-carboxypentanamido>-(4R)-mercapto azetidin-2-one)disulphide

: 69644-78-6
bis[Aad(-Cys-D-Val)]

Guidance literature:: Multi-step reaction with 2 steps

1: selenocysteine, sodium borohydride, DTT / H₂O / 0.67 h

2: O₂m, NH₄OH / 1 h / Ambient temperature

With ammonium hydroxide; sodium tetrahydroborate; DL-dithiothreitol; L-selenocysteine; In water;
DOI:10.1016/S0040-4020(01)91148-2

Reference yield:

: 24325-14-2
(2S)-2-[(phenylmethoxy)carbonyl]aminoadipic acid

: 69644-78-6,94131-56-3
(S)-2-Amino-5-[(R)-2-[(R)-2-(5-amino-5-carboxy-pentanoylamino)-2-((R)-1-carboxy-2-methyl-propylcarbamoyl)-ethyldisulfanyl]-1-((R)-1-carboxy-2-methyl-propylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 50 percent / Et₃N / dimethylformamide / 0 deg C -> room temperature, overnight

2: 64 percent / 1-hydroxybenzotriazole hydrate, dicyclohexylcarbodi-imide / ethyl acetate

3: 98 percent / 0.2M HCl / nitromethane / 5 h / Ambient temperature

4: 71 percent / 1-hydroxybenzotriazole hydrate, dicyclohexylcarbodi-imide / ethyl acetate

5: 1.) Na, liquid NH₃, 2.) air / 2.) pH 8, 2 h

With hydrogenchloride; air; ammonia; sodium; 1-hydroxybenzotriazol-hydrate; triethylamine; dicyclohexyl-carbodiimide; In nitromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1039/P19830000941