(1-Methylpiperidin-3-yl)-diphenylmethanol

Base Information

• Chemical Name: (1-Methylpiperidin-3-yl)-diphenylmethanol
• CAS No.: 109933-30-4
• Molecular Formula: C₁₉H₂₃NO
• Molecular Weight: 281.398
• DSSTox Substance ID: DTXSID901333196
• ChEMBL ID: CHEMBL1564060
• Mol file: 109933-30-4.mol

Synonyms:(1-methylpiperidin-3-yl)-diphenylmethanol;(1-Methyl-piperidin-3-yl)-diphenyl-methanol;Oprea1_639839;109933-30-4;MLS000767106;CHEMBL1564060;DTXSID901333196;HMS2782M13;STL163480;AKOS005715910;SMR000429437;(1-methylpiperidin-3-yl)(diphenyl)methanol;EU-0005501;SR-01000150172;SR-01000150172-1

Chemical Property of (1-Methylpiperidin-3-yl)-diphenylmethanol

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 281.177964357
• Heavy Atom Count: 21
• Complexity: 300

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1CCCC(C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

Technology Process of (1-Methylpiperidin-3-yl)-diphenylmethanol

There total 7 articles about (1-Methylpiperidin-3-yl)-diphenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylmagnesium bromide → (1-Methyl-[3]piperidyl)-diphenyl-methanol (109933-30-4)

Guidance literature:

With diethyl ether;

DOI:10.1021/jo01136a012

Reference yield:

phenyllithium (591-51-5) → (1-Methyl-[3]piperidyl)-diphenyl-methanol (109933-30-4)

Guidance literature:

With diethyl ether;

Reference yield:

arecoline (63-75-2) → (1-Methyl-[3]piperidyl)-diphenyl-methanol (109933-30-4)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: platinum; acetic acid / Hydrogenation

With diethyl ether; acetic acid; platinum;

upstream raw materials:

dihydroarecoline

phenyllithium

arecoline

3-(methoxycarbonyl)-1-methylpyridinium iodide

Downstream raw materials:

3-benzhydrylidene-1-methyl-piperidine