1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane

Base Information

• Chemical Name: 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane
• CAS No.: 4920-72-3
• Molecular Formula: C₁₃H₁₇Br
• Molecular Weight: 253.182
• Mol file: 4920-72-3.mol

Synonyms:

Chemical Property of 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane

There total 4 articles about 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-Dimethyl-2-butene (563-79-1) + bromo(phenyl)carbene (14541-26-5) → 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane (4920-72-3)

Guidance literature:

In 2,2,4-trimethylpentane; at 23 ℃; Rate constant; Irradiation; laser flash photolysis λ^ex:351 nm;

DOI:10.1016/S0040-4039(00)87856-9

Reference yield:

2,3-Dimethyl-2-butene (563-79-1) + benzylidene dibromide (618-31-5) → 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane (4920-72-3)

Guidance literature:

With potassium tert-butylate;

DOI:10.1016/S0040-4020(01)99056-8

Reference yield:

2,3-Dimethyl-2-butene (563-79-1) + 3-bromo-3-phenyl-3H-diazirine (4222-25-7) → 1-bromo-1-phenyl-2,2,3,3-tetramethylcyclopropane (4920-72-3)

Guidance literature:

In neat (no solvent); Irradiation; steady state photolysis λ>300 nm;

DOI:10.1016/S0040-4039(00)87856-9

upstream raw materials:

2,3-Dimethyl-2-butene

benzylidene dibromide

bromo(phenyl)carbene

3-bromo-3-phenyl-3H-diazirine

Downstream raw materials:

2,4-dimethyl-3-phenylpenta-1,3-diene

1,1,2,2-Tetramethyl-3-phenylcyclopropane

1-methoxy-2,2,3,3-tetramethyl-1-phenylcyclopropane

Refernces

• 1、 Turro, Nicholas J.,Okamoto, Masami,Gould, Ian R.,Moss, Robert A.,Lawrynowicz, Witold,Hadel, Linda M.. "Volumes of Activation for the Cycloaddition Reactions of Phenylhalocarbenes to Alkenes". . p. 4973 - 4976. Retrieved 2007/10/02.