methyl-2-<2'(R and S)-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate

Base Information

• Chemical Name: methyl-2-<2'(R and S)-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate
• CAS No.: 95477-53-5
• Molecular Formula: C₁₆H₁₇Cl₃N₂O₅S
• Molecular Weight: 455.746
• Mol file: 95477-53-5.mol

Synonyms:

Chemical Property of methyl-2-<2'(R and S)-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl-2-<2'(R and S)-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate

There total 6 articles about methyl-2-<2'(R and S)-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R,6R)-3-Chloromethyl-3-methyl-7-oxo-6-phenoxycarbonylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester (95477-54-6) → methyl-2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-53-5) + methyl-2-<2'S-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-53-5)

Guidance literature:

With sulfuryl dichloride;

Reference yield:

(2S,3R,6R)-3-Chloromethyl-3-methyl-7-oxo-6-phenoxycarbonylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester (95477-54-6) → methyl-2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-53-5) + methyl-2-<2'S-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-53-5)

Guidance literature:

With sulfuryl dichloride;

Reference yield:

methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-52-4) → methyl-2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-53-5) + methyl-2-<2'S-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate (95477-53-5)

Guidance literature:

With water; for 0.5h;

upstream raw materials:

methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate

(2S,3R,6R)-3-Chloromethyl-3-methyl-7-oxo-6-phenoxycarbonylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester

Downstream raw materials:

methyl 2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-but-2-enoate

methyl 2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-but-2-enoate

methyl 2-<2'S-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-but-2-enoate