2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride

Base Information

Chemical Name:2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride
CAS No.:927869-56-5
Molecular Formula:C10H10ClNO3S
Molecular Weight:259.713
Hs Code.:2933990090
European Community (EC) Number:837-561-3
DSSTox Substance ID:DTXSID00582477
Nikkaji Number:J2.421.423K
Wikidata:Q82473917
Mol file:927869-56-5.mol

Synonyms:927869-56-5;2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride;2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE-7-SULFONYL CHLORIDE;1H-1-Benzazepine-7-sulfonyl chloride, 2,3,4,5-tetrahydro-2-oxo-;2-OXO-1,3,4,5-TETRAHYDRO-1-BENZAZEPINE-7-SULFONYL CHLORIDE;SCHEMBL22400700;DTXSID00582477;GS3124;MFCD11099485;AKOS000431050;AS-43571;CS-0004281;EN300-37069;2-OXO-2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPINE-7-SULFONYLCHLORIDE

Suppliers and Price of 2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-7-SULFONYL CHLORIDE 95.00%
1G
$ 808.89

American Custom Chemicals Corporation
2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-7-SULFONYL CHLORIDE 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-7-SULFONYL CHLORIDE 95.00%
2.5G
$ 1147.43

Alichem
2-Oxo-2,3,4,5-tetrahydro-1h-benzo[b]azepine-7-sulfonylchloride
5g
$ 1025.15

AK Scientific
2-Oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonylchloride
100mg
$ 246.00

Total 3 raw suppliers

Chemical Property of 2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride

Chemical Property:

Vapor Pressure:1E-08mmHg at 25°C
Boiling Point:462.2°C at 760 mmHg
Flash Point:233.3°C
PSA：71.62000
Density:1.417g/cm³
LogP:3.10770
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:259.0069920
Heavy Atom Count:16
Complexity:376

Purity/Quality:

99% ^*data from raw suppliers

2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE-7-SULFONYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC(=C2)S(=O)(=O)Cl)NC(=O)C1

Technology Process of 2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride

There total 2 articles about 2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 4424-80-0
2,3,4,5-tetrahydro-1H-1-benzo[b]azepin-2-one

: 927869-56-5
2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-7-sulfonyl chloride

Guidance literature:: With chlorosulfonic acid; In tetrachloromethane; at 70 ℃; for 3h;
DOI:10.1080/00397910600943493

Reference yield:

: 529-34-0
3,4-dihydronaphthalene-1(2H)-one

: 927869-56-5
2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-7-sulfonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; hydroxylamine hydrochloride / methanol / 17 h / 20 °C / Inert atmosphere

2: polyphosphoric acid / 4.5 h / 120 °C / Inert atmosphere

3: chlorosulfonic acid / tetrachloromethane / 3 h / 70 °C / Inert atmosphere

With chlorosulfonic acid; hydroxylamine hydrochloride; triethylamine; In methanol; tetrachloromethane; 2: |Beckmann Rearrangement;
DOI:10.1021/acs.jmedchem.5b01640