Technology Process of benzyl 4,5,7,8-tetra-O-acetyl-2-bromo-3-deoxy-α-D-manno-2-octulosonate
There total 3 articles about benzyl 4,5,7,8-tetra-O-acetyl-2-bromo-3-deoxy-α-D-manno-2-octulosonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 78 percent / CH2Cl2; petroleum ether / 2 h / Ambient temperature
2: 1.) Molecular Sieves 4A; 2.) titanium tetrabromide / 1.) dichloromethane, ethyl acetate, 60 min, r.t; 2.) dichloromethane, ethyl acetate, 16 h, r.t.
With
4 A molecular sieve; titanium(IV) bromide;
In
dichloromethane; Petroleum ether;
DOI:10.1248/cpb.35.4537
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 78 percent / CH2Cl2; petroleum ether / 2 h / Ambient temperature
2: 1.) Molecular Sieves 4A; 2.) titanium tetrabromide / 1.) dichloromethane, ethyl acetate, 60 min, r.t; 2.) dichloromethane, ethyl acetate, 16 h, r.t.
With
4 A molecular sieve; titanium(IV) bromide;
In
dichloromethane; Petroleum ether;
DOI:10.1248/cpb.35.4537
- Guidance literature:
-
With
4 A molecular sieve; titanium(IV) bromide;
Yield given. Multistep reaction;
1.) dichloromethane, ethyl acetate, 60 min, r.t; 2.) dichloromethane, ethyl acetate, 16 h, r.t.;
DOI:10.1248/cpb.35.4537
