Chemical Property of 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride
Chemical Property:
- Boiling Point:576.5±50.0 °C(Predicted)
- PKA:9.67±0.10(Predicted)
- PSA:33.09000
- Density:1.18
- LogP:8.31590
- Storage Temp.:Store at -20°C
- Solubility.:H2O: ≥13mg/mL
- Purity/Quality:
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97% *data from raw suppliers
MCOPPB Trihydrochloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Uses
A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.