Benzenecarboximidamide, 3-[[(3S)-3-[[(7-methoxy-2-naphthalenyl)sulfonyl]amino]-2-oxo-1-pyrrolidinyl]methyl]-

Base Information

Chemical Name:Benzenecarboximidamide, 3-[[(3S)-3-[[(7-methoxy-2-naphthalenyl)sulfonyl]amino]-2-oxo-1-pyrrolidinyl]methyl]-
CAS No.:186547-01-3
Molecular Formula:C23H24N4O4S
Molecular Weight:452.52606
Hs Code.:
Mol file:186547-01-3.mol

Synonyms:3-[[(3S)-3-[(7-methoxynaphthalen-2-yl)sulfonylamino]-2-oxopyrrolidin-1-yl]methyl]benzenecarboximidamide;BenzenecarboxiMidaMide, 3-[[(3S)-3-[[(7-Methoxy-2-naphthalenyl)sulfonyl]aMino]-2-oxo-1-pyrrolidinyl]Methyl]-

Suppliers and Price of Benzenecarboximidamide, 3-[[(3S)-3-[[(7-methoxy-2-naphthalenyl)sulfonyl]amino]-2-oxo-1-pyrrolidinyl]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
3-[[(3S)-3-[[(7-METHOXY-2-NAPHTHALENYL)SULFONYL]AMINO]-2-OXO-1-PYRROLIDINYL]METHYL]BENZENECARBOXIMIDAMIDE 95.00%
5MG
$ 504.39

Total 1 raw suppliers

Chemical Property of Benzenecarboximidamide, 3-[[(3S)-3-[[(7-methoxy-2-naphthalenyl)sulfonyl]amino]-2-oxo-1-pyrrolidinyl]methyl]-

Chemical Property:

Purity/Quality:: 3-[[(3S)-3-[[(7-METHOXY-2-NAPHTHALENYL)SULFONYL]AMINO]-2-OXO-1-PYRROLIDINYL]METHYL]BENZENECARBOXIMIDAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenecarboximidamide, 3-[[(3S)-3-[[(7-methoxy-2-naphthalenyl)sulfonyl]amino]-2-oxo-1-pyrrolidinyl]methyl]-

There total 14 articles about Benzenecarboximidamide, 3-[[(3S)-3-[[(7-methoxy-2-naphthalenyl)sulfonyl]amino]-2-oxo-1-pyrrolidinyl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135-55-7
7-hydroxynaphthalene-2-sulfonic acid sodium salt

: 186547-01-3
3-[(R)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine

Guidance literature:: Multi-step reaction with 5 steps

1: aq. NaOH / ethanol / 16 h / 20 °C

2: 3.80 g / POCl₃; PCl₅ / 4 h / 120 °C

3: Et₃N / CH₂Cl₂ / 2 h

4: HCl / ethanol / 6 h / 20 °C

5: NH₃ / 24 h

With hydrogenchloride; sodium hydroxide; phosphorus pentachloride; ammonia; triethylamine; trichlorophosphate; In ethanol; dichloromethane; 1: Methylation / 2: Chlorination / 3: Condensation / 4: Addition / 5: amidation;
DOI:10.1021/jm990040h

Reference yield:

: 135-55-7
7-hydroxynaphthalene-2-sulfonic acid sodium salt

: 186547-01-3
3-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine

Guidance literature:: Multi-step reaction with 5 steps

1: aq. NaOH / ethanol / 16 h / 20 °C

2: 3.80 g / POCl₃; PCl₅ / 4 h / 120 °C

3: Et₃N / CH₂Cl₂ / 2 h

4: HCl / ethanol / 6 h / 20 °C

5: NH₃ / 24 h

With hydrogenchloride; sodium hydroxide; phosphorus pentachloride; ammonia; triethylamine; trichlorophosphate; In ethanol; dichloromethane; 1: Methylation / 2: Chlorination / 3: Condensation / 4: Addition / 5: amidation;
DOI:10.1021/jm990040h

Reference yield:

: 56875-60-6
7-Methoxy-2-naphthalenesulfonyl chloride

: 186547-01-3
3-[(R)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 2 h

2: HCl / ethanol / 6 h / 20 °C

3: NH₃ / 24 h

With hydrogenchloride; ammonia; triethylamine; In ethanol; dichloromethane; 1: Condensation / 2: Addition / 3: amidation;
DOI:10.1021/jm990040h