1H-Indazole-3-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]-3-pyridinyl]-2-fluorophenyl]-7-fluoro-

Base Information

• Chemical Name: 1H-Indazole-3-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]-3-pyridinyl]-2-fluorophenyl]-7-fluoro-
• CAS No.: 885591-80-0
• Molecular Formula: C₂₉H₂₃F₂N₇O₂
• Molecular Weight: 539.544
• Mol file: 885591-80-0.mol

Synonyms:1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]pyridin-3-yl]-2-fluorophenyl]-7-fluoroindazole-3-carboxamide;1H-Indazole-3-carboxaMide, 1-(3-aMino-1,2-benzisoxazol-5-yl)-6-[4-[2-[(diMethylaMino)Methyl]-3-pyridinyl]-2-fluorophenyl]-7-fluoro-

Chemical Property of 1H-Indazole-3-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]-3-pyridinyl]-2-fluorophenyl]-7-fluoro-

Chemical Property:

• PSA: 130.81000
• LogP: 5.73090

Purity/Quality:

99% ^*data from raw suppliers

1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-[4-[2-[(DIMETHYLAMINO)METHYL]-3-PYRIDINYL]-2-FLUOROPHENYL]-7-FLU-1H-INDAZOLE-3-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Indazole-3-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]-3-pyridinyl]-2-fluorophenyl]-7-fluoro-

There total 2 articles about 1H-Indazole-3-carboxamide, 1-(3-amino-1,2-benzisoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]-3-pyridinyl]-2-fluorophenyl]-7-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C29H21F3N6O (1007346-66-8) + acetylhydroxamic acid (546-88-3) → 1-(3-amino-benzo[d]isoxazol-5-yl)-6-[4-(2-dimethylaminomethyl-pyridin-3-yl)-2-fluoro-phenyl]-7-fluoro-1H-indazole-3-carboxylic acid amide (885591-80-0)

Guidance literature:

With potassium carbonate; In water; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jm701217r

Reference yield:

→ 1-(3-amino-benzo[d]isoxazol-5-yl)-6-[4-(2-dimethylaminomethyl-pyridin-3-yl)-2-fluoro-phenyl]-7-fluoro-1H-indazole-3-carboxylic acid amide (885591-80-0)

Guidance literature:

upstream raw materials:

C₂₉H₂₁F₃N₆O

acetylhydroxamic acid