Benzenemethanesulfonamide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methyl-

Base Information

Chemical Name:Benzenemethanesulfonamide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methyl-
CAS No.:915192-39-1
Molecular Formula:C23H19F6N3O5S
Molecular Weight:563.477
Hs Code.:
Mol file:915192-39-1.mol

Synonyms:[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methanesulfonamide;BenzeneMethanesulfonaMide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-Methyl-

Suppliers and Price of Benzenemethanesulfonamide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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American Custom Chemicals Corporation
4-[6,8-DIHYDRO-6-OXO-5,9-BIS-(2,2,2-TRIFLUOROETHOXY)-7H-PYRROLO-[3,4-G]QUINOLIN-7-YL]-3-METHYL-BENZENEMETHANE SULFONAMIDE 95.00%
5MG
$ 505.09

Total 3 raw suppliers

Chemical Property of Benzenemethanesulfonamide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methyl-

Chemical Property:

PSA：120.20000
LogP:6.22040

Purity/Quality:

99% ^*data from raw suppliers

4-[6,8-DIHYDRO-6-OXO-5,9-BIS-(2,2,2-TRIFLUOROETHOXY)-7H-PYRROLO-[3,4-G]QUINOLIN-7-YL]-3-METHYL-BENZENEMETHANE SULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenemethanesulfonamide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methyl-

There total 11 articles about Benzenemethanesulfonamide, 4-[6,8-dihydro-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1185886-65-0
1-{4-[8-hydroxy-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methylphenyl}methanesulfonamide

: 915192-39-1
1-{3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]phenyl}methanesulfonamide

: 915192-40-4
1-{3-methyl-4-[8-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]phenyl}methanesulfonamide

: 1185886-66-1
1-{4-[6-hydroxy-8-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methylphenyl}methanesulfonamide

: C₂₃H₂₁F₆N₃O₄S

: 1185886-67-2
C₂₃H₂₁F₆N₃O₆S

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; Inert atmosphere; Reflux; Large scale reaction;
DOI:10.1021/jo901267x

Reference yield: 56.0%

: 1185886-65-0
1-{4-[8-hydroxy-6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methylphenyl}methanesulfonamide

: 1185886-66-1
1-{4-[6-hydroxy-8-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]-3-methylphenyl}methanesulfonamide

: 915192-39-1
1-{3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]phenyl}methanesulfonamide

: 915192-40-4
1-{3-methyl-4-[8-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]phenyl}methanesulfonamide

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃;

Reference yield:

: 915192-31-3
1-(3-methyl-4-nitrophenyl)methanesulfonamide

: 915192-39-1
1-{3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl]phenyl}methanesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen / palladium 10% on activated carbon / ethanol; acetic acid / 3 h / 2068.65 Torr

2: acetic acid / 6.5 h / Heating / reflux

3: lithium borohydride / tetrahydrofuran / -20 - 5 °C

4: triethylsilane; trifluoroacetic acid / dichloromethane / 20 °C

With triethylsilane; lithium borohydride; hydrogen; trifluoroacetic acid; palladium 10% on activated carbon; In tetrahydrofuran; ethanol; dichloromethane; acetic acid;