Tanogitran

Base Information

Chemical Name:Tanogitran
CAS No.:637328-69-9
Molecular Formula:C25H31N7O3
Molecular Weight:477.566
Hs Code.:
UNII:X5QRR6Z56Q
Nikkaji Number:J3.538.630K
Wikidata:Q27293584
NCI Thesaurus Code:C90705
Pharos Ligand ID:ZSTNVYQK8LFV
ChEMBL ID:CHEMBL1270156
Mol file:637328-69-9.mol

Synonyms:Tanogitran;637328-69-9;Tanogitran [INN];UNII-X5QRR6Z56Q;X5QRR6Z56Q;BIBT986;BIBT-986-BS;BIBT-986;N-((2R)-2-(2-((4-Carbamimidoylanilino)methyl)-1-methyl-1H-benzimidazol-5-yl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)glycine;CHEMBL1270156;D0X2NN;SCHEMBL2471738;MAOALPSHCIBFJZ-RUZDIDTESA-N;BDBM50328705;AKOS040749614;2-[[(2R)-2-[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazol-5-yl]-1-oxo-1-pyrrolidin-1-ylpropan-2-yl]amino]acetic acid;J3.538.630K;Q27293584;(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1-(pyrrolidinocarbonyl) -ethyl]-benzimidazole;(R)-2-(4-Amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole;(R)-2-(4-Amidinophenylaminomethyl)-1-methyl-5-[l -(carboxymethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole

Suppliers and Price of Tanogitran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-[(1R)-1-[2-[[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]METHYL]-1-METHYL-1H-BENZIMIDAZOL-5-YL]-1-METHYL-2-OXO-2-(1-PYRROLIDINYL)ETHYL]GLYCINE 95.00%
5MG
$ 503.13

Total 6 raw suppliers

Chemical Property of Tanogitran

Chemical Property:

PSA：149.36000
Density:1.38
LogP:3.18310
XLogP3:-1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:477.24883788
Heavy Atom Count:35
Complexity:781

Purity/Quality:

99% ^*data from raw suppliers

N-[(1R)-1-[2-[[[4-(AMINOIMINOMETHYL)PHENYL]AMINO]METHYL]-1-METHYL-1H-BENZIMIDAZOL-5-YL]-1-METHYL-2-OXO-2-(1-PYRROLIDINYL)ETHYL]GLYCINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC2=C(C=C1)N(C(=N2)CNC3=CC=C(C=C3)C(=N)N)C)(C(=O)N4CCCC4)NCC(=O)O
Isomeric SMILES:C[C@@](C1=CC2=C(C=C1)N(C(=N2)CNC3=CC=C(C=C3)C(=N)N)C)(C(=O)N4CCCC4)NCC(=O)O

Technology Process of Tanogitran

There total 2 articles about Tanogitran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(ethyloxycarbonylmethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole-p-toluenesulphonic acid salt

: 637328-69-9
Tanogitran

Guidance literature:: (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(ethyloxycarbonylmethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole-p-toluenesulphonic acid salt; With potassium hydroxide; In methanol; at 40 ℃; for 2.5h;

With toluene-4-sulfonic acid; In methanol;

Reference yield: 72.0%

: (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(n-propyloxycarbonylmethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole-p-toluenesulphonate

: 637328-69-9
Tanogitran

Guidance literature:: (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(n-propyloxycarbonylmethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole-p-toluenesulphonate; With sodium hydroxide; In methanol; for 3h; Heating / reflux;

With toluene-4-sulfonic acid; In methanol; for 1.5h; Heating / reflux;