1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone

Base Information

Chemical Name:1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone
CAS No.:310415-30-6
Molecular Formula:C23H25FN4O5
Molecular Weight:456.474
Hs Code.:
Mol file:310415-30-6.mol

Synonyms:1-[3-fluoro-4-[4-(2-morpholin-4-yl-5-nitrobenzoyl)piperazin-1-yl]phenyl]ethanone;1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone;Ethanone, 1-[3-fluoro-4-[4-[2-(4-Morpholinyl)-5-nitrobenzoyl]-1-piperazinyl]phenyl]-

Suppliers and Price of 1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone

Chemical Property:

Boiling Point:696.9±55.0 °C(Predicted)
PKA:0.15±0.10(Predicted)
Density:1.339

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone

There total 2 articles about 1-[4-[4-[2-(Morpholin-4-yl)-5-nitrobenzoyl]piperazin-1-yl]-3-fluorophenyl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 110-91-8,99108-56-2
morpholine

: 330636-53-8
1-{3-fluoro-4-[4-(2-fluoro-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanone

: 310415-30-6
1-{4-[4-(2-morpholin-4-yl-5-nitro-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone

Guidance literature:: at 100 ℃; for 0.5h;

Reference yield:

: 4036-83-3
2-(4-morpholinyl)-5-nitrobenzoic acid

: 189763-57-3
1-(3-fluoro-4-(piperazine-1-yl)phenyl)ethane-1-one

: 310415-30-6
1-{4-[4-(2-morpholin-4-yl-5-nitro-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2008.07.086

Reference yield: 80.0%

: 310415-30-6
1-{4-[4-(2-morpholin-4-yl-5-nitro-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone

: 847972-14-9
C₂₃H₂₇FN₄O₃

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; under 760.051 Torr;
DOI:10.1016/j.bmcl.2008.07.086