Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester

Base Information

Chemical Name:Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester
CAS No.:623563-74-6
Molecular Formula:C32H41N3O11
Molecular Weight:643.68144
Hs Code.:
Mol file:623563-74-6.mol

Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester

Synonyms:DMGOTRJCWDJSQX-CHQVSRGASA-N;Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylaMino)-2-oxoethoxy]phenyl]-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-1-oxopropyl]aMino]butoxy]-6-hydroxy-, 1-Methyl ester

Suppliers and Price of Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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American Custom Chemicals Corporation
2-[4-[[(2S)-3-[4-[1-CARBOXY-2-(CYCLOPROPYLAMINO)-2-OXOETHOXY]PHENYL]-2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-1-OXOPROPYL]AMINO]BUTOXY]-6-HYDROXY-1-BENZOIC ACID METHYL ESTER 95.00%
5MG
$ 498.77

Total 3 raw suppliers

Chemical Property of Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester

Chemical Property:

PSA：209.29000
LogP:4.58560

Purity/Quality:

99% ^*data from raw suppliers

2-[4-[[(2S)-3-[4-[1-CARBOXY-2-(CYCLOPROPYLAMINO)-2-OXOETHOXY]PHENYL]-2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-1-OXOPROPYL]AMINO]BUTOXY]-6-HYDROXY-1-BENZOIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester

There total 6 articles about Benzoic acid, 2-[4-[[(2S)-3-[4-[1-carboxy-2-(cyclopropylamino)-2-oxoethoxy]phenyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]amino]butoxy]-6-hydroxy-, 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3978-80-1
Boc-Tyr-OH

: 623563-74-6
2-(4-{2-tert-butoxycarbonylamino-3-[4-(carboxy-cyclopropylcarbamoyl-methoxy)-phenyl]-propionylamino}-butoxy)-6-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: NaHCO₃ / Heating

2: K₂CO₃ / Heating

3: H₂ / Pd/C / ethanol / 760 Torr

4: Et₃N / 0 °C

5: tetrahydrofuran

6: aq. NaOH / ethanol

With sodium hydroxide; hydrogen; sodium hydrogencarbonate; potassium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(03)00725-X

Reference yield:

: 19391-35-6
N-tert-butoxycarbonyl-L-tyrosine benzyl ester

: 623563-74-6
2-(4-{2-tert-butoxycarbonylamino-3-[4-(carboxy-cyclopropylcarbamoyl-methoxy)-phenyl]-propionylamino}-butoxy)-6-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: K₂CO₃ / Heating

2: H₂ / Pd/C / ethanol / 760 Torr

3: Et₃N / 0 °C

4: tetrahydrofuran

5: aq. NaOH / ethanol

With sodium hydroxide; hydrogen; potassium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(03)00725-X

Reference yield:

: 2-[4-(2-benzyloxycarbonyl-2-tert-butoxycarbonylamino-ethyl)-phenoxy]-N-cyclopropyl-malonamic acid ethyl ester

: 623563-74-6
2-(4-{2-tert-butoxycarbonylamino-3-[4-(carboxy-cyclopropylcarbamoyl-methoxy)-phenyl]-propionylamino}-butoxy)-6-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/C / ethanol / 760 Torr

2: Et₃N / 0 °C

3: tetrahydrofuran

4: aq. NaOH / ethanol

With sodium hydroxide; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1016/S0960-894X(03)00725-X