5'-O-deoxythymidine

Base Information

Chemical Name:5'-O-deoxythymidine
CAS No.:138395-79-6
Molecular Formula:C₂₄H₃₁N₃O₈
Molecular Weight:489.525
Hs Code.:

5'-O-<N-(t-butyloxycarbonyl)-L-phenylalanyl>deoxythymidine

Synonyms:

Suppliers and Price of 5'-O-deoxythymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-O-deoxythymidine

Chemical Property:

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Technology Process of 5'-O-deoxythymidine

There total 3 articles about 5'-O-deoxythymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 138395-81-0
3'-O-deoxythymidine

: 138395-79-6
5'-O-deoxythymidine

Guidance literature:: With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; In pyridine; for 24h; Ambient temperature;

Reference yield: 42.0%

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 138395-79-6
5'-O-deoxythymidine

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In N,N,N,N,N,N-hexamethylphosphoric triamide; for 12h; other substrate, other method for the aminoacylation of nucleosides;
DOI:10.1016/S0040-4039(00)92384-0

Reference yield:

: 3674-06-4
Boc-Phe-ONSu

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 138395-81-0
3'-O-deoxythymidine

: 138395-79-6
5'-O-deoxythymidine

: 138395-83-2
(S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid (2R,3S,5R)-2-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

Guidance literature:: subtilisin; In N,N-dimethyl-formamide; at 45 ℃; for 120h; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(00)92384-0