Chemical Property of Toceranib
Chemical Property:
- Boiling Point:596.8±50.0 °C(Predicted)
- PKA:11.70±0.20(Predicted)
- PSA：77.23000
- Density:1.293
- LogP:3.55570
- Storage Temp.:room temp
- Solubility.:DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
- XLogP3:2.4
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:5
- Exact Mass:396.19615422
- Heavy Atom Count:29
- Complexity:663
- Purity/Quality:
-
99%, *data from raw suppliers
Toceranib *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O
- Isomeric SMILES:CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O
-
Uses
Toceranib is a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors, mixed m
ammary carcinomas, soft tissue sarcomas, and multiple myeloma. Labelled Toceranib, a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors,
mixed mammary carcinomas, soft tissue sarcomas, and multiple myeloma. Toceranib is a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors, mixed mammary carcinomas, soft tissue sarcomas, and multiple myeloma.
