(3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one

Base Information

Chemical Name:(3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one
CAS No.:160549-09-7
Molecular Formula:C₂₂H₄₂O₃
Molecular Weight:354.574
Hs Code.:
European Community (EC) Number:605-212-2
DSSTox Substance ID:DTXSID001175058
Nikkaji Number:J1.235.228J

Synonyms:DTXSID001175058;(3S,4R,6R)-3-Hexyltetrahydro-4-hydroxy-6-undecyl-2H-pyran-2-one;(3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one;160549-09-7

Suppliers and Price of (3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
XLogP3:8.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:15
Exact Mass:354.31339520
Heavy Atom Count:25
Complexity:329

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCCCCCCCC1CC(C(C(=O)O1)CCCCCC)O
Isomeric SMILES:CCCCCCCCCCC[C@@H]1C[C@H]([C@@H](C(=O)O1)CCCCCC)O

Technology Process of (3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one

There total 18 articles about (3S)-3beta-Hexyl-4alpha-hydroxy-6beta-undecyltetrahydro-2H-pyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112-54-9
Dodecanal

: 160549-09-7
3-hexyl-3,4,5,6-tetrahydro-4β-hydroxy-6-undecyl-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: 92 percent / Zn; NH₄Cl / tetrahydrofuran; H₂O / 1 h

2.1: 86 percent / NaH / tetrahydrofuran / 12 h / 20 °C

3.1: ozone / CH₂Cl₂ / 2 h

3.2: 81 percent / triphenylphosphine / CH₂Cl₂ / 40 h / 0 °C

4.1: 45 percent / Zn / benzene / 2 h / ultrasound

5.1: 72 percent / pyridinium chlorochromate; NaOAc / CH₂Cl₂ / 0 °C

6.1: 68 percent / TBAF / tetrahydrofuran / 6 h / -78 °C

7.1: 70 percent / ZnBH₄ / diethyl ether / 12 h / -20 °C

8.1: porcine pancreatic lipase; molecular sieves 4 Angstroem / diethyl ether / 48 h

With zinc(II) tetrahydroborate; porcine pancreatic lipase; 4 A molecular sieve; tetrabutyl ammonium fluoride; sodium acetate; sodium hydride; ammonium chloride; ozone; pyridinium chlorochromate; zinc; In tetrahydrofuran; diethyl ether; dichloromethane; water; benzene; 1.1: Alkylation / 2.1: silylation / 3.1: ozonolysis / 3.2: Reduction / 4.1: Reformatsky reaction / 5.1: Oxidation / 6.1: desilylation / 7.1: Reduction / 8.1: Cyclization;
DOI:10.1021/jo990370+

Reference yield:

: 112-53-8
1-dodecyl alcohol

: 160549-09-7
3-hexyl-3,4,5,6-tetrahydro-4β-hydroxy-6-undecyl-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 9 steps

1.1: 90 percent / pyridinium chlorochromate / CH₂Cl₂ / 3 h / 0 °C

2.1: 92 percent / Zn; NH₄Cl / tetrahydrofuran; H₂O / 1 h

3.1: 86 percent / NaH / tetrahydrofuran / 12 h / 20 °C

4.1: ozone / CH₂Cl₂ / 2 h

4.2: 81 percent / triphenylphosphine / CH₂Cl₂ / 40 h / 0 °C

5.1: 45 percent / Zn / benzene / 2 h / ultrasound

6.1: 72 percent / pyridinium chlorochromate; NaOAc / CH₂Cl₂ / 0 °C

7.1: 68 percent / TBAF / tetrahydrofuran / 6 h / -78 °C

8.1: 70 percent / ZnBH₄ / diethyl ether / 12 h / -20 °C

9.1: porcine pancreatic lipase; molecular sieves 4 Angstroem / diethyl ether / 48 h

With zinc(II) tetrahydroborate; porcine pancreatic lipase; 4 A molecular sieve; tetrabutyl ammonium fluoride; sodium acetate; sodium hydride; ammonium chloride; ozone; pyridinium chlorochromate; zinc; In tetrahydrofuran; diethyl ether; dichloromethane; water; benzene; 1.1: Oxidation / 2.1: Alkylation / 3.1: silylation / 4.1: ozonolysis / 4.2: Reduction / 5.1: Reformatsky reaction / 6.1: Oxidation / 7.1: desilylation / 8.1: Reduction / 9.1: Cyclization;
DOI:10.1021/jo990370+

Reference yield:

: 2623-82-7,70610-87-6
2-bromooctanoic acid

: 160549-09-7
3-hexyl-3,4,5,6-tetrahydro-4β-hydroxy-6-undecyl-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 6 steps

1: 88 percent / H₂SO₄ / 4 h / Heating

2: 45 percent / Zn / benzene / 2 h / ultrasound

3: 72 percent / pyridinium chlorochromate; NaOAc / CH₂Cl₂ / 0 °C

4: 68 percent / TBAF / tetrahydrofuran / 6 h / -78 °C

5: 70 percent / ZnBH₄ / diethyl ether / 12 h / -20 °C

6: porcine pancreatic lipase; molecular sieves 4 Angstroem / diethyl ether / 48 h

With zinc(II) tetrahydroborate; porcine pancreatic lipase; 4 A molecular sieve; sulfuric acid; tetrabutyl ammonium fluoride; sodium acetate; pyridinium chlorochromate; zinc; In tetrahydrofuran; diethyl ether; dichloromethane; benzene; 1: Esterification / 2: Reformatsky reaction / 3: Oxidation / 4: desilylation / 5: Reduction / 6: Cyclization;
DOI:10.1021/jo990370+