N-desmethyl-chlorprothixen

Base Information

• Chemical Name: N-desmethyl-chlorprothixen
• CAS No.: 522-22-5
• Molecular Formula: C₁₇H₁₆ClNS
• Molecular Weight: 301.84

Synonyms:

Chemical Property of N-desmethyl-chlorprothixen

Chemical Property:

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Technology Process of N-desmethyl-chlorprothixen

There total 1 articles about N-desmethyl-chlorprothixen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Chlorprothixen (4695-61-8) → N-desmethyl-chlorprothixen (522-22-5) + Chlorprothixenoxid (10120-63-5,16260-06-3) + C16H14ClNS + C17H16ClNOS + C16H14ClNOS

Guidance literature:

With NADPH; In aq. buffer; at 30 ℃; pH=7.3; Enzymatic reaction;

DOI:10.1021/acs.joc.1c01407

Reference yield:

N-desmethyl-chlorprothixen (522-22-5) + 4-(3-(piperidin-1-yl)propoxy)benzaldehyde (82625-46-5) → C32H37ClN2OS

Guidance literature:

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2008.09.012

upstream raw materials:

Chlorprothixen

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