2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester
CAS No.:778595-07-6
Molecular Formula:C₃₀H₄₃NO₈
Molecular Weight:545.673
Hs Code.:

2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Synonyms:

Suppliers and Price of 2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

There total 8 articles about 2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2,2-dimethyl-propionic acid 3-(tert-butyl-dimethyl-silanyloxy)-5-[2-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-2-(tetrahydro-pyran-2-yloxy)-ethyl]-hex-5-enyl ester

: 778595-07-6
2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; Yield given;
DOI:10.1016/S0040-4039(99)00209-9

Reference yield:

: 88920-24-5
p-methoxybenzyloxy acetic acid

: 778595-07-6
2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Guidance literature:: Multi-step reaction with 7 steps

2: DAST

3: 81 percent / BrCCl₃, DBU

4: 90 percent / DIBAL / CH₂Cl₂ / 0.17 h / -78 °C

5: 1.) (R,R)-1,2-diamino-1,2-diphenylethane bis-sulfonamide, BBr₃ / 1.) CH₂Cl₂, 12 h, 2.) CH₂Cl₂, -78 deg C

6: PPTs / CH₂Cl₂

7: TBAF / tetrahydrofuran

With Bromotrichloromethane; (R,R)-1,2-diamino-1,2-diphenylethane bis-sulfonamide; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; boron tribromide; diisobutylaluminium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 4,4'-diaminostilbene-2,2'-disulfonic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(99)00209-9

Reference yield:

: 224578-16-9
2-(4-Methoxy-benzyloxymethyl)-oxazole-4-carbaldehyde

: 778595-07-6
2,2-Dimethyl-propionic acid (3R,7R)-3-hydroxy-7-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-5-methylene-7-(tetrahydro-pyran-2-yloxy)-heptyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) (R,R)-1,2-diamino-1,2-diphenylethane bis-sulfonamide, BBr₃ / 1.) CH₂Cl₂, 12 h, 2.) CH₂Cl₂, -78 deg C

2: PPTs / CH₂Cl₂

3: TBAF / tetrahydrofuran

With (R,R)-1,2-diamino-1,2-diphenylethane bis-sulfonamide; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; boron tribromide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(99)00209-9