8-Fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide

Base Information

Chemical Name:8-Fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide
CAS No.:36720-87-3
Molecular Formula:C₁₇H₁₅FNOP
Molecular Weight:299.284
Hs Code.:
NSC Number:164948
DSSTox Substance ID:DTXSID50304247

Synonyms:36720-87-3;NSC164948;DTXSID50304247;8-fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide;NSC-164948

Suppliers and Price of 8-Fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8-Fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide

Chemical Property:

Vapor Pressure:7.92E-12mmHg at 25°C
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:299.08752926
Heavy Atom Count:21
Complexity:437

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CP(=O)(CC2=C1NC3=C2C=C(C=C3)F)C4=CC=CC=C4

Technology Process of 8-Fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide

There total 3 articles about 8-Fluoro-2-phenyl-1,3,4,5-tetrahydrophosphinino[4,3-b]indole 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36720-83-9
8-fluoro-2-phenyl-2,3,4,5-tetrahydro-1H-phosphinino[4,3-b]indole

: 36720-87-3
8-fluoro-2-phenyl-2,3,4,5-tetrahydro-1H-phosphinino[4,3-b]indole 2-oxide

Guidance literature:: With oxygen; In diethyl ether; hexane;
DOI:10.1021/jo00799a052

Reference yield:

: 823-85-8
4-fluorophenyhydrazine hydrochloride

: 36720-87-3
8-fluoro-2-phenyl-2,3,4,5-tetrahydro-1H-phosphinino[4,3-b]indole 2-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: (i) AcOH, (ii) aq. HCl

2: O₂ / diethyl ether; hexane

With oxygen; In diethyl ether; hexane;
DOI:10.1021/jo00799a052

Reference yield:

: 23855-87-0
1-phenyl-4-phosphorinanone

: 36720-87-3
8-fluoro-2-phenyl-2,3,4,5-tetrahydro-1H-phosphinino[4,3-b]indole 2-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: (i) AcOH, (ii) aq. HCl

2: O₂ / diethyl ether; hexane

With oxygen; In diethyl ether; hexane;
DOI:10.1021/jo00799a052