3H-1,2,4-Triazol-3-one, 5-butyl-2-(4-chlorophenyl)-1,2-dihydro-

Base Information

Chemical Name:3H-1,2,4-Triazol-3-one, 5-butyl-2-(4-chlorophenyl)-1,2-dihydro-
CAS No.:127683-63-0
Molecular Formula:C₁₂H₁₄ClN₃O
Molecular Weight:251.716
Hs Code.:
Mol file:127683-63-0.mol

Synonyms:5-Butyl-2-(4-chlorophenyl)-1,2-dihydro-3H-1,2,4-triazol-3-one

Suppliers and Price of 3H-1,2,4-Triazol-3-one, 5-butyl-2-(4-chlorophenyl)-1,2-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3H-1,2,4-Triazol-3-one, 5-butyl-2-(4-chlorophenyl)-1,2-dihydro-

Chemical Property:

PSA：50.68000
LogP:2.55660

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3H-1,2,4-Triazol-3-one, 5-butyl-2-(4-chlorophenyl)-1,2-dihydro-

There total 2 articles about 3H-1,2,4-Triazol-3-one, 5-butyl-2-(4-chlorophenyl)-1,2-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 999-09-7
ethyl valerimidate

: 127683-63-0
5-Butyl-2-(4-chloro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / Et₃N / CH₂Cl₂ / 2 h / Ambient temperature

2: 2.) Et₃N / 1.) toluene, from 45 deg C to 50 deg C, 1.5 h, 2.) toluene, 90 deg C, overnight

With triethylamine; In dichloromethane;
DOI:10.1021/jm00069a015

Reference yield:

: 83483-30-1
ethyl N-carbethoxyvalerimidate

: 1073-69-4
N-4-chlorophenylhydrazine

: 127683-63-0
5-Butyl-2-(4-chloro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one

Guidance literature:: With triethylamine; Multistep reaction; 1.) toluene, from 45 deg C to 50 deg C, 1.5 h, 2.) toluene, 90 deg C, overnight;
DOI:10.1021/jm00069a015

Reference yield:

: 127683-63-0
5-Butyl-2-(4-chloro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one

: 5-Butyl-2-(4-chloro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, from 40 deg C to 50 deg C, 20 min, 2.) DMF, 35 deg C, 2.5 h

2: glacial acetic acid / H₂O / 65 °C

With sodium hydride; acetic acid; In water;
DOI:10.1021/jm00069a015