2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester

Base Information

Chemical Name:2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester
CAS No.:720720-14-9
Molecular Formula:C13H19NO3
Molecular Weight:237.299
Hs Code.:
Mol file:720720-14-9.mol

Synonyms:(4-AMINOMETHYL-PHENOXY)-ACETIC ACID TERT-BUTYL ESTER;2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester;Acetic acid, 2-[4-(aminomethyl)phenoxy]-, 1,1-dimethylethyl ester

Suppliers and Price of 2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl2-(4-(aminomethyl)phenoxy)acetate 95+%
5g
$ 1632.00

Crysdot
tert-Butyl2-(4-(aminomethyl)phenoxy)acetate 95+%
1g
$ 465.00

Total 6 raw suppliers

Chemical Property of 2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester

Chemical Property:

Boiling Point:340℃
Flash Point:128℃
PSA：61.55000
Density:1.081
LogP:2.56610

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl2-(4-(aminomethyl)phenoxy)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester

There total 1 articles about 2-[4-(Aminomethyl)phenoxy]acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 720720-13-8
tert-butyl [4-(hydroxyiminomethyl)phenoxy]acetate

: 720720-14-9
tert-butyl (4-aminomethylphenoxy)acetate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; water; at 20 ℃; for 3h; under 3750.38 Torr;

Reference yield: 48.0%

: 690998-35-7
6-(4-fluoro-3-methyl-benzylcarbamoyl)-pyrimidine-4-carboxylic acid

: 720720-14-9
tert-butyl (4-aminomethylphenoxy)acetate

: tert-Butyl [4-({[6-(4-fluoro-3-methylbenzylcarbamoyl)pyrimidine-4-carbonyl]amino}methyl)phenoxy]acetate

Guidance literature:: 6-(4-fluoro-3-methyl-benzylcarbamoyl)-pyrimidine-4-carboxylic acid; With O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 0.5h;

tert-butyl (4-aminomethylphenoxy)acetate; With N-ethylmorpholine;; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 12h;

Reference yield:

: 720720-14-9
tert-butyl (4-aminomethylphenoxy)acetate

: tert-butyl 2-(4-(((4-(tert-butyl)benzyl)((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)amino)methyl)phenoxy)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / chloroform; methanol

2: potassium carbonate / N,N-dimethyl-formamide / 12 h / 80 °C

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.1c01527