3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole

Base Information

• Chemical Name: 3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole
• CAS No.: 1120215-07-7
• Molecular Formula: C6H8BrNO3
• Molecular Weight: 222.04
• Hs Code.: 2934999090
• Mol file: 1120215-07-7.mol

Synonyms:3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole

Chemical Property of 3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole

Chemical Property:

• Boiling Point: 263.1±50.0 °C(Predicted)
• PSA: 40.05000
• Density: 2.04±0.1 g/cm3(Predicted)
• LogP: 0.29220

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole

There total 1 articles about 3-Bromo-5-[1,3]dioxolan-2-yl-4,5-dihydroisoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-vinyl-1,3-dioxolane (3984-22-3) + N-dibromomethylidenehydroxylamine (74213-24-4) → 3-bromo-4-(1,3-dioxolan-2-yl)-4,5-dihydro-isoxazole + 3-bromo-5-(1,3-dioxolan-2-yl)-4,5-dihydro-isoxazole (1120215-07-7)

Guidance literature:

With potassium hydrogencarbonate; In water; N,N-dimethyl-formamide; at -10 - 20 ℃; for 2h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol9000284

upstream raw materials:

2-vinyl-1,3-dioxolane

N-dibromomethylidenehydroxylamine

Refernces