N-(4-azido-3-nitro-phenyl)-acetamide

Base Information

• Chemical Name: N-(4-azido-3-nitro-phenyl)-acetamide
• CAS No.: 6086-30-2
• Molecular Formula: C₈H₇N₅O₃
• Molecular Weight: 221.175
• Mol file: 6086-30-2.mol

Synonyms:

Chemical Property of N-(4-azido-3-nitro-phenyl)-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-azido-3-nitro-phenyl)-acetamide

There total 6 articles about N-(4-azido-3-nitro-phenyl)-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-acetyl-p-phenylenediamine (122-80-5) → N-(4-azido-3-nitro-phenyl)-acetamide (6086-30-2)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid / 0.25 h / Heating

2: 60percent nitric acid, conc. sulfuric acid / 1.) 0 deg C, 10 min, 2.) RT, 30 min

3: conc. sulfuric acid / 0.25 h / 100 °C

4: 1.) aq. HCl, NaNO₂, 2.) aq. NaN₃, sodium acetate / 1.) 0 deg C, 15 min

With hydrogenchloride; sodium azide; sulfuric acid; nitric acid; sodium acetate; sodium nitrite; In acetic acid;

DOI:10.1021/jm00010a023

Reference yield:

1,4-phenylenediamine (106-50-3) → N-(4-azido-3-nitro-phenyl)-acetamide (6086-30-2)

Guidance literature:

Multi-step reaction with 5 steps

1: acetic acid / 0.25 h / Heating

2: acetic acid / 0.25 h / Heating

3: 60percent nitric acid, conc. sulfuric acid / 1.) 0 deg C, 10 min, 2.) RT, 30 min

4: conc. sulfuric acid / 0.25 h / 100 °C

5: 1.) aq. HCl, NaNO₂, 2.) aq. NaN₃, sodium acetate / 1.) 0 deg C, 15 min

With hydrogenchloride; sodium azide; sulfuric acid; nitric acid; sodium acetate; sodium nitrite; In acetic acid;

DOI:10.1021/jm00010a023

Reference yield:

4-acetylamino-1-amino-2-nitrobenzene (6086-29-9) → N-(4-azido-3-nitro-phenyl)-acetamide (6086-30-2)

Guidance literature:

Multistep reaction; (i) NO, AcOH, (ii) aq. NaN3;

DOI:10.1039/j39660000971

upstream raw materials:

4-acetylamino-1-amino-2-nitrobenzene

N,N'-diacetyl-1,4-phenylenediamine

nitro-p-phenylenediamine N¹,N⁴-diacetate

1,4-phenylenediamine

Refernces