Chemical Property of N-[3-(2,1,3-benzothiadiazol-5-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
Chemical Property:
- Vapor Pressure:3.22E-16mmHg at 25°C
- Refractive Index:1.772
- Boiling Point:638.9 °C at 760 mmHg
- PKA:6.71±0.30(Predicted)
- Flash Point:340.2 °C
- PSA：149.61000
- Density:1.538 g/cm3
- LogP:5.06300
- Solubility.:≥22.45 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
- XLogP3:4.2
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:9
- Rotatable Bond Count:5
- Exact Mass:448.07761612
- Heavy Atom Count:31
- Complexity:711
- Purity/Quality:
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99%, *data from raw suppliers
N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide, *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4
- Recent ClinicalTrials:Study of XL147 (SAR245408) in Advanced or Recurrent Endometrial Carcinoma
- Recent EU Clinical Trials:A Phase 1/2 Study of XL147 Administered in Combination with Trastuzumab or Paclitaxel and
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Description
XL147 analog is an analog of XL147 .
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Uses
XL147 analogue is one of Pyrimidine derivatives as JAK-2 inhibitors in combination with other agents and their use in the treatment of diseases.
