N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine

Base Information

Chemical Name:N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
CAS No.:916603-07-1
Molecular Formula:C17H16FN5
Molecular Weight:309.34
Hs Code.:2921499090
DSSTox Substance ID:DTXSID10580580
Metabolomics Workbench ID:56151
Wikidata:Q27118121
Mol file:916603-07-1.mol

Synonyms:916603-07-1;N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine;CZC-8004;N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine;Dianilinopyrimidine_01;CZC8004;2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine;CZC-00008004;N(2)-[4-(aminomethyl)phenyl]-5-fluoro-N(4)-phenylpyrimidine-2,4-diamine;Dianilinopyrimidine-01;C17H16FN5;SCHEMBL4276330;CHEBI:39072;DTXSID10580580;AMY16234;BCP01985;MFCD16251195;N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine;AKOS016006994;NCGC00387026-01;AS-16202;HY-111138;CS-0034386;A860275;J-523400;Q27118121;Target-5 (Kinase Probe Tool, APM-1)/Dianilinopyrimidine_01;N~2~-[4-(Aminomethyl)phenyl]-5-fluoro-N~4~-phenylpyrimidine-2,4-diamine

Suppliers and Price of N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
10mg
$ 500.00

Medical Isotopes, Inc.
N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
2.5 mg
$ 890.00

Matrix Scientific
N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine 95+%
250mg
$ 183.00

DC Chemicals
Dianilinopyrimidine_01 >98%
1 g
$ 3000.00

DC Chemicals
Dianilinopyrimidine_01 >98%
100 mg
$ 750.00

DC Chemicals
Dianilinopyrimidine_01 >98%
250 mg
$ 1500.00

Crysdot
N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine 95+%
10g
$ 2822.00

Crysdot
N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine 95+%
1g
$ 455.00

ChemScene
CZC-8004 99.51%
5mg
$ 110.00

ChemScene
CZC-8004 99.51%
10mg
$ 180.00

Total 24 raw suppliers

Chemical Property of N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine

Chemical Property:

Boiling Point:514.1 °C at 760 mmHg
PKA:9.14±0.10(Predicted)
Flash Point:264.7 °C
PSA：75.86000
Density:1.332 g/cm³
LogP:4.40790
Storage Temp.:-20°
Solubility.:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming)
XLogP3:2.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:309.13897369
Heavy Atom Count:23
Complexity:342

Purity/Quality:

97% ^*data from raw suppliers

N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN
Description CZC-8004 (916603-07-1) is a pan-specific kinase inhibitor. May be coupled to sepharose via its amino-side chain for affinity chromatography applications1.
Uses A novel enzyme-interacting compounds using immobilized broad-spectrum ligands CZC-8004 is an aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be immobilized to capture and purify these enzymes.

Technology Process of N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine

There total 1 articles about N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: