2,3,5-Trimethyl-6-bromopyridine

Base Information

• Chemical Name: 2,3,5-Trimethyl-6-bromopyridine
• CAS No.: 34595-91-0
• Molecular Formula: C8H10BrN
• Molecular Weight: 200.0757
• Mol file: 34595-91-0.mol

Synonyms:6-Brom-2,4-dimethyl-2-acetoxy-cyclohexa-3,5-dien-1-on;6-Brom-2.3.5-trimethylpyridin;2,4-Cyclohexadien-1-one,6-(acetyloxy)-2-bromo-4,6-dimethyl;6-acetoxy-2-bromo-4,6-dimethylcyclohexa-2,4-dien-1-one;2-bromo-3,5,6-trimethyl-pyridine;

Chemical Property of 2,3,5-Trimethyl-6-bromopyridine

Chemical Property:

• Refractive Index: 1.542
• Boiling Point: 255.212 °C at 760 mmHg
• Flash Point: 108.149 °C
• PSA: 12.89000
• Density: 1.355 g/cm³
• LogP: 2.76930

Purity/Quality:

99% Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5-Trimethyl-6-bromopyridine

There total 3 articles about 2,3,5-Trimethyl-6-bromopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-3,5,6-trimethylpyridine (56705-18-1) → 2,3,5-trimethyl-6-bromopyridine (34595-91-0)

Guidance literature:

With bromine; sodium nitrite; In water; at 4 ℃; Temperature; Acidic conditions;

Reference yield:

methyllithium (917-54-4) + 2,6-dibromo-3,5-dimethylpyridine (117846-58-9) → 2,3,5-trimethyl-6-bromopyridine (34595-91-0)

Guidance literature:

In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 17h;

Reference yield:

→ 2,3,5-trimethyl-6-bromopyridine (34595-91-0)

Guidance literature:

2.3.5-Trimethylpyridin (9), Bromierung mit N.N-Dibromisocyanursaeure, Fluorsulfonsaeure;

upstream raw materials:

2-Amino-3,5,6-trimethylpyridine

methyllithium

2,6-dibromo-3,5-dimethylpyridine