(IR,2S)-N-Pyrrolidinyl norephedrine HCL

Base Information

• Chemical Name: (IR,2S)-N-Pyrrolidinyl norephedrine HCL
• CAS No.: 210558-66-0
• Molecular Formula: C13H19NO.HCl
• Molecular Weight: 241.761
• Mol file: 210558-66-0.mol

Synonyms:(IR,2S)-N-Pyrrolidinyl norephedrine HCL;(1R,2S)-1-Phenyl-2-(1-pyrrolidinyl)propan-1-ol hydrochloride;

Chemical Property of (IR,2S)-N-Pyrrolidinyl norephedrine HCL

Chemical Property:

• PSA: 23.47000
• Density: 1.351
• LogP: 2.94420

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (IR,2S)-N-Pyrrolidinyl norephedrine HCL

There total 2 articles about (IR,2S)-N-Pyrrolidinyl norephedrine HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(1R/S,2S)-1-phenyl-2-(pyrrolidin-1-yl)propan-1-ol → (1R,2S)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride (210558-66-0)

Guidance literature:

With hydrogenchloride; In ethanol; at 20 - 30 ℃; for 1h; Reflux;

Reference yield:

→ (1R,2S)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride (210558-66-0)

Guidance literature:

Reference yield: 100.0%

(1R,2S)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride (210558-66-0) → (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol (56571-91-6,56571-92-7,123620-80-4,127641-25-2)

Guidance literature:

With hydrogenchloride; In water; toluene; Reflux;

Downstream raw materials:

(S)-(-)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride

Refernces

• 1、 -. "Efficient synthesis of a chiral mediator". . . Retrieved 2008/06/13.