L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R,R)]-

Base Information

Chemical Name:L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R*,R*)]-
CAS No.:69980-30-9
Molecular Formula:C₂₆H₄₁N₃O₇
Molecular Weight:507.627
Hs Code.:
DSSTox Substance ID:DTXSID901107911

Synonyms:DTXSID901107911;69980-30-9;L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R*,R*)]-

Suppliers and Price of L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R*,R*)]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R*,R*)]-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:15
Exact Mass:507.29445066
Heavy Atom Count:36
Complexity:720

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC(C(CC(=O)O)O)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1

Technology Process of L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R*,R*)]-

There total 3 articles about L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]-, [S-(R*,R*)]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3S,4S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-methyl-butyrylamino]-3-hydroxy-6-methyl-heptanoic acid ethyl ester

: 69980-30-9
carbobenzoxy-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1021/jm00111a054

Reference yield:

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 69980-30-9
carbobenzoxy-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (i) ClCO₂iBu, (ii) /BRN= 6710267/, Et₃N, (iii) (catalytic hydrogenation)

DOI:10.7164/antibiotics.25.689