2,2,5,7,7,10-Hexamethyl-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromene

Base Information

• Chemical Name: 2,2,5,7,7,10-Hexamethyl-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromene
• CAS No.: 19206-86-1
• Molecular Formula: C₁₈H₂₆O₂
• Molecular Weight: 274.403
• NSC Number: 139489
• DSSTox Substance ID: DTXSID90300869
• Nikkaji Number: J401.767F
• Wikidata: Q82044271
• Mol file: 19206-86-1.mol

Synonyms:19206-86-1;2,2,5,7,7,10-hexamethyl-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromene;NSC139489;DTXSID90300869;NSC-139489

Chemical Property of 2,2,5,7,7,10-Hexamethyl-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromene

Chemical Property:

• Vapor Pressure: 2.4E-05mmHg at 25°C
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 274.193280068
• Heavy Atom Count: 20
• Complexity: 338

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C2CCC(OC2=C(C3=C1OC(CC3)(C)C)C)(C)C

Technology Process of 2,2,5,7,7,10-Hexamethyl-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromene

There total 8 articles about 2,2,5,7,7,10-Hexamethyl-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,3,4,7,8,9-hexahydro-2,2,5,7,7,10-hexamethylbenzo<1,2-b:4,5-b'>dipyran(1+) dibromoiodate → 2,3,4,7,8,9-hexahydro-2,2,5,7,7,10-hexamethylbenzo<1,2-b:4,5-b'>dipyran (19206-86-1)

Guidance literature:

With sodium thiosulfate; In dichloromethane; for 72h; Product distribution;

DOI:10.1016/S0040-4020(01)86189-5

Reference yield: 30.0%

2-methyl-3-buten-2-ol (115-18-4) + 2,5-dimethylhydroquinone (615-90-7) → 2,3,4,7,8,9-hexahydro-2,2,5,7,7,10-hexamethylbenzo<1,2-b:4,5-b'>dipyran (19206-86-1) + 6-hydroxy-2,2,5,8-tetramethylchroman (19206-87-2)

Guidance literature:

2-methyl-3-buten-2-ol; 2,5-dimethylhydroquinone; With formic acid; In tetrahydrofuran; at 100 ℃; for 3h;

With hydrogenchloride; In methanol; at 60 ℃; for 0.333333h; Further stages.;

DOI:10.1021/jo0706832

Reference yield:

2,3,4,7,8,9-hexahydro-2,2,5,7,7,10-hexamethylbenzo<1,2-b:4,5-b'>dipyran (19206-86-1) → 2,3,4,7,8,9-hexahydro-2,2,5,7,7,10-hexamethylbenzo<1,2-b:4,5-b'>dipyran radical cation (19206-86-1)

Guidance literature:

With oxygen; trifluoroacetic acid; In dichloromethane;

DOI:10.1039/f19827802743

upstream raw materials:

2,5-dimethylhydroquinone

3-methyl-2-buten-1-ol

2-methyl-3-buten-2-ol

2,5-Dimethyl-1,4-benzoquinone