2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid

Base Information

Chemical Name:2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid
CAS No.:124328-41-2
Molecular Formula:C₁₁H₉F₃N₂O₅
Molecular Weight:306.198
Hs Code.:
DSSTox Substance ID:DTXSID201180493

Synonyms:DTXSID201180493;2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid;124328-41-2

Suppliers and Price of 2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:306.04635588
Heavy Atom Count:21
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(CC(=O)O)NC(=O)C(F)(F)F)[N+](=O)[O-]

Technology Process of 2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid

There total 2 articles about 2-Nitro-beta-[(2,2,2-trifluoroacetyl)amino]benzenepropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 552-89-6
2-nitro-benzaldehyde

: 124328-41-2
acide trifluoroacetylamino-3 (nitro-2 phenyl)-3 propionique

Guidance literature:: Multi-step reaction with 2 steps

1: NH₄OAc / ethanol / 6 h / Heating

2: 0.5 h / Heating

With ammonium acetate; In ethanol;

Reference yield:

: 5678-48-8,732242-02-3,756814-14-9
3-amino-3-(2-nitrophenyl)propionic acid

: 407-25-0
trifluoroacetic anhydride

: 124328-41-2
acide trifluoroacetylamino-3 (nitro-2 phenyl)-3 propionique

Guidance literature:: for 0.5h; Heating;

Reference yield:

: 124328-41-2
acide trifluoroacetylamino-3 (nitro-2 phenyl)-3 propionique

: 136788-00-6
4-(2-Nitro-phenyl)-imidazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) triethylamine, ethyl chloroformate, 2.) sodium azide / 1.) acetone, 0-5 deg C,, 30 min, 2.) acetone, H₂O, 1 h

2: H₂O / CHCl₃ / 0.5 h / Heating

With sodium azide; water; chloroformic acid ethyl ester; triethylamine; In chloroform;