2-Hydroxy-N,N,5-trimethylbenzamide

Base Information

Chemical Name:2-Hydroxy-N,N,5-trimethylbenzamide
CAS No.:100245-03-2
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID70544648
Wikidata:Q82421837
Mol file:100245-03-2.mol

Synonyms:100245-03-2;2-HYDROXY-N,N,5-TRIMETHYLBENZAMIDE;SCHEMBL12261016;DTXSID70544648;AKOS000212238;MB09412;Z68248211

Suppliers and Price of 2-Hydroxy-N,N,5-trimethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Hydroxy-N,N,5-trimethylbenzamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:191

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)O)C(=O)N(C)C

Technology Process of 2-Hydroxy-N,N,5-trimethylbenzamide

There total 3 articles about 2-Hydroxy-N,N,5-trimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 6935-65-5
3,N,N-trimethylbenzamide

: N,N-dimethyl-2-hydroxy-3-methylbenzamide

: 100245-03-2
2-(dimethylaminocarbonyl)-4-methylphenol

Guidance literature:: 3,N,N-trimethylbenzamide; With dirhodium tetraacetate; triethylamine triflouroacetate; trifluoroacetic acid; trifluoroacetic anhydride; at 20 ℃; Electrolysis; Inert atmosphere; Schlenk technique;

With water; sodium hydrogencarbonate; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.202017359

Reference yield:

: 1711-06-4
3-Methylbenzoyl chloride

: N,N-dimethyl-2-hydroxy-3-methylbenzamide

: 100245-03-2
2-(dimethylaminocarbonyl)-4-methylphenol

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine

2.1: dirhodium tetraacetate; triethylamine triflouroacetate; trifluoroacetic acid; trifluoroacetic anhydride / 20 °C / Electrolysis; Inert atmosphere; Schlenk technique

2.2: Inert atmosphere; Schlenk technique

With dirhodium tetraacetate; triethylamine triflouroacetate; triethylamine; trifluoroacetic acid; trifluoroacetic anhydride;
DOI:10.1002/anie.202017359