25-R-<26-(2)H3>-cholecalciferol

Base Information

• Chemical Name: 25-R-<26-(2)H3>-cholecalciferol
• CAS No.: 77286-64-7
• Molecular Formula: C₂₇H₄₄O
• Molecular Weight: 387.622
• Mol file: 77286-64-7.mol

Synonyms:

Chemical Property of 25-R-<26-(2)H3>-cholecalciferol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 25-R-<26-(2)H3>-cholecalciferol

There total 5 articles about 25-R-<26-(2)H3>-cholecalciferol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

R-3-<(2)H3>-methylbutan-1-ol (77248-15-8) → 25-R-<26-(2)H3>-cholecalciferol (72409-70-2,77286-64-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 48percent HBr / H₂SO₄

3: pyridine

With hydrogen bromide; In pyridine; sulfuric acid;

DOI:10.1016/S0040-4039(00)77862-2

Reference yield:

R-<(2)H3>-isopropyl malonic acid (77248-11-4) → 25-R-<26-(2)H3>-cholecalciferol (72409-70-2,77286-64-7)

Guidance literature:

Multi-step reaction with 5 steps

2: 48percent HBr / H₂SO₄

4: pyridine

With hydrogen bromide; In pyridine; sulfuric acid;

DOI:10.1016/S0040-4039(00)77862-2

Reference yield:

C5H8(2)H3Br (77248-16-9) → 25-R-<26-(2)H3>-cholecalciferol (72409-70-2,77286-64-7)

Guidance literature:

Multi-step reaction with 3 steps

2: pyridine

In pyridine;

DOI:10.1016/S0040-4039(00)77862-2

upstream raw materials:

C₃₈H₅₂⁽²⁾H₃N₃O₇S

R-3-<(2)H3>-methylbutan-1-ol

C₅H₈⁽²⁾H₃Br

R-<(2)H3>-isopropyl malonic acid