(2-Bromo-5-nitrophenyl)hydrazine

Base Information

• Chemical Name: (2-Bromo-5-nitrophenyl)hydrazine
• CAS No.: 100367-78-0
• Molecular Formula: C6H6BrN3O2
• Molecular Weight: 232.037
• DSSTox Substance ID: DTXSID30695009
• Wikidata: Q82623983
• Mol file: 100367-78-0.mol

Synonyms:(2-Bromo-5-nitrophenyl)hydrazine;100367-78-0;Hydrazine, (2-bromo-5-nitrophenyl)-;1-(2-BROMO-5-NITROPHENYL)HYDRAZINE;2-Bromo-5-nitrophenylhydrazine;SCHEMBL3374367;DTXSID30695009;YGKPMXOMDNPDHO-UHFFFAOYSA-N;(2-Bromo-5-nitrophenyl)-hydrazine;AKOS017553082;FT-0710091;D88193;EN300-201138;J-500655

Chemical Property of (2-Bromo-5-nitrophenyl)hydrazine

Chemical Property:

• Boiling Point: 331.1±32.0 °C(Predicted)
• PKA: 3.75±0.10(Predicted)
• PSA: 83.87000
• Density: 1.869±0.06 g/cm3(Predicted)
• LogP: 2.93940
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 230.96434
• Heavy Atom Count: 12
• Complexity: 173

Purity/Quality:

95+% ^*data from raw suppliers

1-(2-bromo-5-nitrophenyl)hydrazine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1[N+](=O)[O-])NN)Br

Technology Process of (2-Bromo-5-nitrophenyl)hydrazine

There total 3 articles about (2-Bromo-5-nitrophenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-bromo 5-nitroaniline (10403-47-1) → (2-bromo-5-nitrophenyl)hydrazine (100367-78-0)

Guidance literature:

2-bromo 5-nitroaniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 3h;

With hydrogenchloride; tin(ll) chloride; In water; at 20 ℃; for 2h;

Reference yield:

→ (2-bromo-5-nitrophenyl)hydrazine (100367-78-0)

Guidance literature:

With hydrogenchloride; sodium sulfite;

Reference yield:

→ (2-bromo-5-nitrophenyl)hydrazine (100367-78-0)

Guidance literature:

upstream raw materials:

2-bromo 5-nitroaniline

Downstream raw materials:

2-(2-bromo-5-nitrophenyl)-5-n-butyl-2,4-dihydro-3H-1,2,4-triazol-3-one

Refernces

• 1、 Liu, Jing-Bo,Li, Yu-Xin,Zhang, Xiu-Lan,Hua, Xue-Wen,Wu, Chang-Chun,Wei, Wei,Wan, Ying-Ying,Cheng, Dan-Dan,Xiong, Li-Xia,Yang, Na,Song, Hai-Bin,Li, Zheng-Ming. "Novel Anthranilic Diamide Scaffolds Containing N-Substituted Phenylpyrazole as Potential Ryanodine Receptor Activators". . p. 3697 - 3704. Retrieved 2016/06/01.
• 2、 -. "Substituted tetrahydro-1H-pyrido[4,3-b]indoles as serotonin receptors agonists and antagonists". Page/Page column 28. . Retrieved 2010/11/25.