2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

Base Information

Chemical Name:2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane
CAS No.:287978-81-8
Molecular Formula:C₂₉H₃₀O₆
Molecular Weight:474.554
Hs Code.:

Synonyms:

Suppliers and Price of 2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

There total 12 articles about 2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115936-35-1
3,6-anhydro-7-O-benzyl-1,2-dideoxy-4,5-O-isopropylidene-D-altro-hept-1-enitol

: 287978-81-8
2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

Guidance literature:: Multi-step reaction with 6 steps

1: 81 percent / aq. H₂SO₄ / dioxane / 2 h / Heating

2: 83 percent / O₂; Cu(I)Cl; Pd(II)Cl₂ / acetonitrile; H₂O / 2 h / 20 °C

3: 87 percent / pyridine / 3 h / 20 °C

4: 29 percent / H₂ / Pd/C / 6 h / 20 °C / 760 Torr

5: pyridine / 8 h / 20 °C

6: 0.21 g / pyridine / 1 h / 20 °C

With pyridine; copper(l) iodide; sulfuric acid; hydrogen; oxygen; palladium dichloride; palladium on activated charcoal; In 1,4-dioxane; water; acetonitrile; 1: Hydrolysis / 2: Oxidation / 3: silylation / 4: Hydrogenolysis / 5: Substitution / 6: Acetylation;

Reference yield:

: 144651-34-3,144732-47-8
3,6-anhydro-1,2:4,5-di-O-isopropylidene-D-glycero-D-manno-heptitol

: 287978-81-8
2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

Guidance literature:: Multi-step reaction with 10 steps

1: 91 percent / NaH / dimethylformamide / 1 h / 20 °C

2: 79 percent / aq. AcOH / 8 h / 20 °C

3: 86 percent / Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

4: 77 percent / NaI / butan-2-one / 14 h / Heating

5: 81 percent / aq. H₂SO₄ / dioxane / 2 h / Heating

6: 83 percent / O₂; Cu(I)Cl; Pd(II)Cl₂ / acetonitrile; H₂O / 2 h / 20 °C

7: 87 percent / pyridine / 3 h / 20 °C

8: 29 percent / H₂ / Pd/C / 6 h / 20 °C / 760 Torr

9: pyridine / 8 h / 20 °C

10: 0.21 g / pyridine / 1 h / 20 °C

With pyridine; copper(l) iodide; sulfuric acid; hydrogen; oxygen; sodium hydride; acetic acid; triethylamine; sodium iodide; palladium dichloride; palladium on activated charcoal; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; butanone; 1: benzylation / 2: Hydrolysis / 3: Substitution / 4: Elimination / 5: Hydrolysis / 6: Oxidation / 7: silylation / 8: Hydrogenolysis / 9: Substitution / 10: Acetylation;

Reference yield:

: 250598-85-7
3,6-anhydro-7-O-benzyl-1,2:4,5-di-O-isopropylidene-D-glycero-D-manno-heptitol

: 287978-81-8
2S,3R,4R,6R,8R/S-3-acetyloxy-8-methyloxy-4-(triphenylmethylenoxy)methyl-1,5-dioxabicyclo[3.3.0]octane

Guidance literature:: Multi-step reaction with 9 steps

1: 79 percent / aq. AcOH / 8 h / 20 °C

2: 86 percent / Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

3: 77 percent / NaI / butan-2-one / 14 h / Heating

4: 81 percent / aq. H₂SO₄ / dioxane / 2 h / Heating

5: 83 percent / O₂; Cu(I)Cl; Pd(II)Cl₂ / acetonitrile; H₂O / 2 h / 20 °C

6: 87 percent / pyridine / 3 h / 20 °C

7: 29 percent / H₂ / Pd/C / 6 h / 20 °C / 760 Torr

8: pyridine / 8 h / 20 °C

9: 0.21 g / pyridine / 1 h / 20 °C

With pyridine; copper(l) iodide; sulfuric acid; hydrogen; oxygen; acetic acid; triethylamine; sodium iodide; palladium dichloride; palladium on activated charcoal; In 1,4-dioxane; dichloromethane; water; acetonitrile; butanone; 1: Hydrolysis / 2: Substitution / 3: Elimination / 4: Hydrolysis / 5: Oxidation / 6: silylation / 7: Hydrogenolysis / 8: Substitution / 9: Acetylation;