Technology Process of C33H28F3N7O2
There total 4 articles about C33H28F3N7O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
piperidine;
In
ethanol;
at 80 ℃;
for 2h;
DOI:10.1021/ml200261d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium 10% on activated carbon; hydrogen / acetic acid / 20 °C
2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
3: piperidine / ethanol / 2 h / 80 °C
With
piperidine; palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU;
In
ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/ml200261d
- Guidance literature:
-
Multi-step reaction with 6 steps
1: hydrogenchloride / water; acetic acid / 110 °C
2: sulfuric acid / 80 °C
3: palladium diacetate; caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / 1,4-dioxane / 110 °C
4: palladium 10% on activated carbon; hydrogen / acetic acid / 20 °C
5: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
6: piperidine / ethanol / 2 h / 80 °C
With
piperidine; hydrogenchloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; palladium diacetate; caesium carbonate; N-ethyl-N,N-diisopropylamine; HATU; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
1,4-dioxane; ethanol; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/ml200261d