2-Acetamido-1-hydroxy-1-(4-nitrophenyl)-2-propene

Base Information

• Chemical Name: 2-Acetamido-1-hydroxy-1-(4-nitrophenyl)-2-propene
• CAS No.: 100061-01-6
• Molecular Formula: C₁₁H₁₂N₂O₄
• Molecular Weight: 236.227
• European Community (EC) Number: 634-510-5
• NSC Number: 102942
• Mol file: 100061-01-6.mol

Synonyms:NSC102942;NCIOpen2_007293;2-ACETAMIDO-1-HYDROXY-1-(4-NITROPHENYL)-2-PROPENE;AKOS024332128;NSC-102942

Chemical Property of 2-Acetamido-1-hydroxy-1-(4-nitrophenyl)-2-propene

Chemical Property:

• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 236.07970687
• Heavy Atom Count: 17
• Complexity: 316

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC(=C)C(C1=CC=C(C=C1)[N+](=O)[O-])O

Technology Process of 2-Acetamido-1-hydroxy-1-(4-nitrophenyl)-2-propene

There total 1 articles about 2-Acetamido-1-hydroxy-1-(4-nitrophenyl)-2-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[1-(4-nitro-benzoyl)-vinyl]-acetamide (6627-80-1) → N-[1-(α-hydroxy-4-nitro-benzyl)-vinyl]-acetamide (100061-01-6)

Guidance literature:

With sodium tetrahydroborate; ethanol;

Reference yield:

N-[1-(α-hydroxy-4-nitro-benzyl)-vinyl]-acetamide (100061-01-6) → 2,4-dimethyl-5-(4-nitro-phenyl)-oxazole (23000-11-5)

Guidance literature:

With 1,4-dioxane; hydrogenchloride;

Reference yield:

sulfuric acid (7664-93-9) + N-[1-(α-hydroxy-4-nitro-benzyl)-vinyl]-acetamide (100061-01-6) → 2,4-dimethyl-5-(4-nitro-phenyl)-oxazole (23000-11-5)

Guidance literature:

upstream raw materials:

N-[1-(4-nitro-benzoyl)-vinyl]-acetamide

Downstream raw materials:

1-acetoxy-1-(4-nitro-phenyl)-acetone

1-<(4-nitro)-phenyl>-1,2-propandione

bis-(4-pyruvoyl-phenyl)-diazene-N-oxide

2,4-dimethyl-5-(4-nitro-phenyl)-oxazole