ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

Base Information

Chemical Name:ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate
CAS No.:147740-01-0
Molecular Formula:C₁₀H₁₂N₂O₂
Molecular Weight:192.217
Hs Code.:
DSSTox Substance ID:DTXSID60596813
Wikidata:Q82492168
Mol file:147740-01-0.mol

Synonyms:ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate;147740-01-0;Ethyl 5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate;ethyl 5,7-dihydropyrrolo[3,4-b]pyridine-6-carboxylate;Ethyl5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate;SCHEMBL1328894;DTXSID60596813;PCBKEVNPKSZQFU-UHFFFAOYSA-N;AKOS006332672;DA-38328;CS-0328692;J-521138

Suppliers and Price of ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate 95+%
1g
$ 299.00

Chemenu
ethyl5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate 95%
1g
$ 282.00

American Custom Chemicals Corporation
ETHYL-5H-PYRROLO[3,4-B]PYRIDINE-6(7H)-CARBOXYLATE 95.00%
5MG
$ 497.21

Alichem
Ethyl5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate
1g
$ 909.49

AK Scientific
Ethyl5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate
1g
$ 2811.00

AK Scientific
Ethyl5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate
250mg
$ 1157.00

Total 8 raw suppliers

Chemical Property of ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

Chemical Property:

Vapor Pressure:0.000652mmHg at 25°C
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:192.089877630
Heavy Atom Count:14
Complexity:220

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)N1CC2=C(C1)N=CC=C2

Technology Process of ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

There total 2 articles about ethyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: (N-ethoxycarbonyl-N-propargylaminomethyl)-pyrazine

: 147740-01-0
ethyl 5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate

: 147740-04-3
ethyl 1H,2H,3H-pyrrolo[3,4-c]pyridine-2-carboxylate

Guidance literature:: In various solvent(s); at 180 ℃;
DOI:10.1016/j.bmcl.2006.06.023

Reference yield:

: 2-(N-ethoxycarbonyl-N-propargylaminomethyl)-pyrimidine

: 147740-01-0
ethyl 5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate

Guidance literature:: In 5,5-dimethyl-1,3-cyclohexadiene;

Reference yield:

: 147740-01-0
ethyl 5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate

: 344459-88-7
C₁₈H₁₈FN₇O₄

Guidance literature:: Multi-step reaction with 9 steps

1.1: 97 percent / aq. HCl / Heating

2.1: 94 percent / DIPEA / dimethylformamide / 60 °C

3.1: HCOONH₄ / Pd/C / tetrahydrofuran; methanol

4.1: aq. NaHCO₃ / acetone

5.1: nBuLi / tetrahydrofuran / -78 °C

5.2: 92 percent / tetrahydrofuran / -78 - 20 °C

6.1: 95 percent / Et₃N / dimethylformamide

7.1: dimethylformamide / 50 °C

8.1: hydrazine / methanol / Heating

9.1: 24 percent / methanol / Heating

With hydrogenchloride; n-butyllithium; ammonium formate; sodium hydrogencarbonate; triethylamine; N-ethyl-N,N-diisopropylamine; hydrazine; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.bmcl.2006.06.023