{2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

Base Information

Chemical Name:{2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester
CAS No.:896719-67-8
Molecular Formula:C₄₇H₆₅N₉O₆Si₂
Molecular Weight:908.261
Hs Code.:

{2-amino-6-benzyloxy-9-[4-(<i>tert</i>-butyl-dimethyl-silanyloxy)-5-(<i>tert</i>-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9<i>H</i>-purin-8-yl}-(1-methyl-6-phenyl-1<i>H</i>-imidazo[4,5-<i>b</i>]pyridin-2-yl)-carbamic acid <i>tert</i>-butyl ester

Synonyms:

Suppliers and Price of {2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

There total 1 articles about {2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 896719-66-7
C₆₈H₈₃N₉O₈Si₂

: 896719-67-8
{2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: With trichloroacetic acid; In methanol; dichloromethane;
DOI:10.1021/tx050296s

Reference yield:

: 896719-67-8
{2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

: 896719-68-9
N-(O⁶-benzyl-N²-phenoxyacetyl-2'-deoxyguanosin-8-yl)-N-t-butoxycarbonyl-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 0 °C

2: triethylamine trihydrogenfluoride complex / tetrahydrofuran

With pyridine; triethylamine tris(hydrogen fluoride); In tetrahydrofuran;
DOI:10.1021/tx050296s

Reference yield:

: 896719-67-8
{2-amino-6-benzyloxy-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-9H-purin-8-yl}-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

: 896719-69-0
[6-benzyloxy-9-{5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2-(2-phenoxy-acetylamino)-9H-purin-8-yl]-(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 0 °C

2: triethylamine trihydrogenfluoride complex / tetrahydrofuran

3: Li₂CO₃; lutidine / 20 °C

With pyridine; lutidine; lithium carbonate; triethylamine tris(hydrogen fluoride); In tetrahydrofuran;
DOI:10.1021/tx050296s