Technology Process of NN-bis-(3,4-dihydroxyphenethyl)amine hydrochloride
There total 7 articles about NN-bis-(3,4-dihydroxyphenethyl)amine hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
ethanol;
for 2h;
Yield given;
DOI:10.1039/P19810002016
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 70 percent / lithium aluminium hydride / tetrahydrofuran / 1.25 h / Heating
2: sodium hydrogen carbonate / CH2Cl2; H2O / 1.5 h
3: 75 percent / diborane / tetrahydrofuran / 0.5 h / Heating
4: hydrogen, conc. hydrochloric acid / 10percent palladium-charcoal / ethanol / 2 h
With
hydrogenchloride; lithium aluminium tetrahydride; hydrogen; sodium hydrogencarbonate; diborane;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane; water;
DOI:10.1039/P19810002016
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 76 percent / potassium hydroxide, water / ethane-1,2-diol / 18 h / Heating
2: oxalyl chloride, DMF / benzene / 1 h / 20 °C
3: sodium hydrogen carbonate / CH2Cl2; H2O / 1.5 h
4: 75 percent / diborane / tetrahydrofuran / 0.5 h / Heating
5: hydrogen, conc. hydrochloric acid / 10percent palladium-charcoal / ethanol / 2 h
With
hydrogenchloride; potassium hydroxide; oxalyl dichloride; water; hydrogen; sodium hydrogencarbonate; N,N-dimethyl-formamide; diborane;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane; water; ethylene glycol; benzene;
DOI:10.1039/P19810002016
