Technology Process of 2-(m-iodophenyl)ethylamine hydrochloride
There total 1 articles about 2-(m-iodophenyl)ethylamine hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3-iodophenyl)acetonitrile;
With
borane-THF;
at 70 ℃;
for 2h;
Inert atmosphere;
With
hydrochloric acid diethyl ether;
In
ethanol;
at 0 ℃;
for 0.0833333h;
Inert atmosphere;
DOI:10.3390/molecules21091160
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium tris(acetoxy)borohydride / methanol / 20 °C / Inert atmosphere
2: dmap / methanol / 0.25 h / 20 °C / Inert atmosphere
3: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 1.5 h / 85 °C / Inert atmosphere
4: [18F]fluoride ion, cyclotron produced, NCA; tetraethylammonium bicarbonate; tetrakis(pyridine)copper(II) bis(trifluoromethanesulfonate) / N,N-dimethyl-formamide / Inert atmosphere; Heating
5: hydroxylamine hydrochloride / ethanol; water / 0.17 h / 100 °C / Microwave irradiation; Inert atmosphere; Enzymatic reaction
With
dmap; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(pyridine)copper(II) bis(trifluoromethanesulfonate); hydroxylamine hydrochloride; potassium acetate; sodium tris(acetoxy)borohydride; tetraethylammonium bicarbonate; [18F]fluoride ion, cyclotron produced, NCA;
In
methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.3390/molecules21091160
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium tris(acetoxy)borohydride / methanol / 20 °C / Inert atmosphere
2: dmap / methanol / 0.25 h / 20 °C / Inert atmosphere
With
dmap; sodium tris(acetoxy)borohydride;
In
methanol;
DOI:10.3390/molecules21091160
