Technology Process of 5-fluoro-4-tosyloxypentyl pivalate
There total 5 articles about 5-fluoro-4-tosyloxypentyl pivalate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) bis(tributyltin) oxide, 2.) caesium fluoride / 1.) toluene, reflux, 3 h, 2.) DMF, 40 deg C, 40 h
2: 85 percent / NH3 (gas) / methanol / 17 h / Ambient temperature
3: 1.) bis(tributyltin) oxide, 2.) triethylamine, 4-(dimethylamino)pyridine (DMAP) / 1.) toluene, reflux, 17 h, 2.) toluene, 65 deg C, 24 h
With
dmap; ammonia; triethylamine; cesium fluoride; bis(tri-n-butyltin)oxide;
In
methanol;
DOI:10.1039/P19930002107
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / NH3 (gas) / methanol / 17 h / Ambient temperature
2: 1.) bis(tributyltin) oxide, 2.) triethylamine, 4-(dimethylamino)pyridine (DMAP) / 1.) toluene, reflux, 17 h, 2.) toluene, 65 deg C, 24 h
With
dmap; ammonia; triethylamine; bis(tri-n-butyltin)oxide;
In
methanol;
DOI:10.1039/P19930002107
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) bis(tributyltin) oxide, 2.) caesium fluoride / 1.) toluene, reflux, 3 h, 2.) DMF, 40 deg C, 40 h
2: 85 percent / NH3 (gas) / methanol / 17 h / Ambient temperature
3: 1.) bis(tributyltin) oxide, 2.) triethylamine, 4-(dimethylamino)pyridine (DMAP) / 1.) toluene, reflux, 17 h, 2.) toluene, 65 deg C, 24 h
With
dmap; ammonia; triethylamine; cesium fluoride; bis(tri-n-butyltin)oxide;
In
methanol;
DOI:10.1039/P19930002107
