1-<1-<2-ethyl>-3-piperidinyl>ethanone

Base Information

Chemical Name:1-<1-<2-ethyl>-3-piperidinyl>ethanone
CAS No.:143747-54-0
Molecular Formula:C₂₂H₂₅Cl₂NO₂
Molecular Weight:406.352
Hs Code.:

1-<1-<2-<bis(4-chlorophenyl)methoxy>ethyl>-3-piperidinyl>ethanone

Synonyms:

Suppliers and Price of 1-<1-<2-ethyl>-3-piperidinyl>ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-<1-<2-ethyl>-3-piperidinyl>ethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-<1-<2-ethyl>-3-piperidinyl>ethanone

There total 8 articles about 1-<1-<2-ethyl>-3-piperidinyl>ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026500-24-2
3-Acetyl-1-{2-[bis-(4-chloro-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid

: 143747-54-0
1-<1-<2-ethyl>-3-piperidinyl>ethanone

Guidance literature:: With sodium dihydrogenphosphate; In ethanol; for 2h; Heating;
DOI:10.1021/jm00100a032

Reference yield:

: 90-97-1
4,4'-dichlorobenzophenone

: 143747-54-0
1-<1-<2-ethyl>-3-piperidinyl>ethanone

Guidance literature:: Multi-step reaction with 7 steps

1: conc. H₂SO₄ / toluene / 2 h / 85 - 90 °C

2: K₂CO₃ / acetonitrile / 15 h / Heating

3: 2 N aq. LiOH / methanol / 64 h / Ambient temperature

4: 86 percent / diethyl ether

5: 1.) LDA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 16 h

6: 1 N aq. LiOH / methanol / 72 h / Ambient temperature

7: 1.6 g / aq. NaH₂PO₄ / ethanol / 2 h / Heating

With lithium hydroxide; sodium dihydrogenphosphate; sulfuric acid; potassium carbonate; lithium diisopropyl amide; In methanol; diethyl ether; ethanol; toluene; acetonitrile;
DOI:10.1021/jm00100a032

Reference yield:

: 221916-05-8
1-bromo-2-[bis(4-chlorophenyl)methoxy]ethane

: 143747-54-0
1-<1-<2-ethyl>-3-piperidinyl>ethanone

Guidance literature:: Multi-step reaction with 6 steps

1: K₂CO₃ / acetonitrile / 15 h / Heating

2: 2 N aq. LiOH / methanol / 64 h / Ambient temperature

3: 86 percent / diethyl ether

4: 1.) LDA / 1.) THF, -78 deg C, 30 min, 2.) THF, from -78 deg C to RT, 16 h

5: 1 N aq. LiOH / methanol / 72 h / Ambient temperature

6: 1.6 g / aq. NaH₂PO₄ / ethanol / 2 h / Heating

With lithium hydroxide; sodium dihydrogenphosphate; potassium carbonate; lithium diisopropyl amide; In methanol; diethyl ether; ethanol; acetonitrile;
DOI:10.1021/jm00100a032