2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride

Base Information

Chemical Name:2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride
CAS No.:85575-42-4
Molecular Formula:C₁₄H₂₀N₄*ClH
Molecular Weight:280.801
Hs Code.:

Synonyms:

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Chemical Property of 2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride

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Technology Process of 2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride

There total 4 articles about 2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85575-39-9
2-(N-chloroacetyl-N-benzyl)aminoimidazole

: 85575-42-4
2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine, molecular sieves / CH₂Cl₂ / 16 h / 80 °C

2: BH₃ / tetrahydrofuran / 14 h / Ambient temperature

3: 2N-HCl / 30 h / Heating

With hydrogenchloride; molecular sieve; borane; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/jhet.5570190630

Reference yield:

: 85575-40-2
2-(N-dimethylaminoacetyl-N-benzyl)aminoimidazole

: 85575-42-4
2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: BH₃ / tetrahydrofuran / 14 h / Ambient temperature

2: 2N-HCl / 30 h / Heating

With hydrogenchloride; borane; In tetrahydrofuran;
DOI:10.1002/jhet.5570190630

Reference yield:

: 85575-38-8
2-<(phenylmethyl)amino>imidazole hydrochloride

: 85575-42-4
2-(N-2-dimethylaminoethyl-N-benzyl)aminoimidazole hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 16 h / 80 °C

2: triethylamine, molecular sieves / CH₂Cl₂ / 16 h / 80 °C

3: BH₃ / tetrahydrofuran / 14 h / Ambient temperature

4: 2N-HCl / 30 h / Heating

With hydrogenchloride; molecular sieve; borane; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/jhet.5570190630