2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone

Base Information

• Chemical Name: 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone
• CAS No.: 76142-15-9
• Molecular Formula: C₂₀H₂₂O₆
• Molecular Weight: 358.391
• Mol file: 76142-15-9.mol

Synonyms:

Chemical Property of 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone

There total 3 articles about 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxychalcone (76142-12-6) → 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone (76142-15-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; Yield given;

Reference yield:

piperonal (120-57-0,30024-74-9) → 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone (76142-15-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent aq. NaOH / ethanol / 1 h / 45 °C

2: H₂ / 10 percent Pd-C / ethyl acetate

With sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; ethyl acetate;

Reference yield:

1-(2-hydroxy-4,6-dimethoxy-3,5-dimethylphenyl)ethanone (21722-31-6) → 2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxydihydrochalcone (76142-15-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent aq. NaOH / ethanol / 1 h / 45 °C

2: H₂ / 10 percent Pd-C / ethyl acetate

With sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; ethyl acetate;

upstream raw materials:

2'-hydroxy-4',6'-dimethoxy-3',5'-dimethyl-3,4-methylenedioxychalcone

piperonal

1-(2-hydroxy-4,6-dimethoxy-3,5-dimethylphenyl)ethanone