N-[(4-Methylphenyl)carbamoyl]phosphoramidic dichloride

Base Information

• Chemical Name: N-[(4-Methylphenyl)carbamoyl]phosphoramidic dichloride
• CAS No.: 101252-13-5
• Molecular Formula: C8H9Cl2N2O2P
• Molecular Weight: 267.051
• DSSTox Substance ID: DTXSID20573645
• Nikkaji Number: J1.911.602F
• Wikidata: Q82462434
• Mol file: 101252-13-5.mol

Synonyms:101252-13-5;N-[(4-Methylphenyl)carbamoyl]phosphoramidic dichloride;DTXSID20573645

Chemical Property of N-[(4-Methylphenyl)carbamoyl]phosphoramidic dichloride

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 265.9778699
• Heavy Atom Count: 15
• Complexity: 274

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NC(=O)NP(=O)(Cl)Cl

Technology Process of N-[(4-Methylphenyl)carbamoyl]phosphoramidic dichloride

There total 1 articles about N-[(4-Methylphenyl)carbamoyl]phosphoramidic dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isocyanatophosphonic dichloride (870-30-4) + p-toluidine (106-49-0,12221-03-3) → N-4-methylphenylureidophosphoryl dichloride (101252-13-5)

Guidance literature:

Reference yield: 80.0%

N-4-methylphenylureidophosphoryl dichloride (101252-13-5) + ethylenediamine (107-15-3,85404-18-8) → 2-(N-4-methyl-phenylureido)-1,3,2-diazaphospholane-2-oxide

Guidance literature:

In dichloromethane; at 0 - 20 ℃;

DOI:10.1007/s00044-016-1527-9

Reference yield: 80.0%

N-4-methylphenylureidophosphoryl dichloride (101252-13-5) + benzyl-methyl-amine (103-67-3) → benzylmethylammonium (3-(4-methylphenyl)ureido)(benzylmethylamino)phosphinate (1394907-49-3)

Guidance literature:

In acetonitrile; at 0 ℃; for 4h; Inert atmosphere;

DOI:10.2478/s11696-012-0177-8

upstream raw materials:

isocyanatophosphonic dichloride

p-toluidine

Downstream raw materials:

5,5-dimethyl-2-(N-4-methylphenylureido)-1,3,2-diazaphosphorinane-2-oxide

5,5-dimethyl-2-(N-4-methylphenylureido)-1,3,2-dioxaphosphorinane-2-oxide

2-(N-4-methylphenylureido)-1,3,2-oxazaphosphorinane-2-oxide

benzylmethylammonium (3-(4-methylphenyl)ureido)(benzylmethylamino)phosphinate