3-Amino-2-nitro-benzo[b]thiophene

Base Information

• Chemical Name: 3-Amino-2-nitro-benzo[b]thiophene
• CAS No.: 10133-36-5
• Molecular Formula: C₈H₆N₂O₂S
• Molecular Weight: 194.214
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID50390908
• Nikkaji Number: J653.016H
• Wikidata: Q82188045
• Mol file: 10133-36-5.mol

Synonyms:2-nitro-1-benzothiophen-3-amine;10133-36-5;3-Amino-2-nitro-benzo[b]thiophene;2-NITRO-BENZO[B]THIOPHEN-3-YLAMINE;SCHEMBL9404612;2-Nitrobenzo[b]thiophen-3-amine;DTXSID50390908;3-amino-2-nitrobenzo[b]thiophene;QUKCPSYNLDHLNI-UHFFFAOYSA-N;AKOS004903209;FT-0723805

Chemical Property of 3-Amino-2-nitro-benzo[b]thiophene

Chemical Property:

• PSA: 100.08000
• LogP: 3.49610
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 194.01499861
• Heavy Atom Count: 13
• Complexity: 219

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-AMINO-2-NITRO-BENZO[B]THIOPHENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=C(S2)[N+](=O)[O-])N

Technology Process of 3-Amino-2-nitro-benzo[b]thiophene

There total 12 articles about 3-Amino-2-nitro-benzo[b]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-bromo-2-nitro-1-benzothiophene (17402-78-7) → 2-nitro-3-aminobenzothiophene (10133-36-5)

Guidance literature:

With ammonium hydroxide; In ethanol; at 70 ℃; for 24h; Sealed tube;

Reference yield: 87.0%

bromonitromethane (563-70-2) + 2-cyanothiophenol (34761-11-0) → 2-nitro-3-aminobenzothiophene (10133-36-5)

Guidance literature:

With sodium hydroxide; In ethanol;

Reference yield: 84.0%

bromonitromethane (563-70-2) + 2-(2-Cyano-ethylsulfanyl)-benzonitrile (107699-02-5) → 2-nitro-3-aminobenzothiophene (10133-36-5)

Guidance literature:

With sodium hydroxide; In water; N,N-dimethyl-formamide; at 17 ℃; for 2h;

upstream raw materials:

2,2 dithiobis(benzonitrile)

sodium nitromethane

3-bromo-2-nitro-1-benzothiophene

bromonitromethane